All posts by imreal

Health: Addiction

Workit Health Announces New Board Member to Support New Phase of Growth

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Logo: Workit Health

Workit Health logo

2019 was a big year for Workit Health in terms of growth and partnerships, and Ben Slocum joining our team further validates Workit Health’s value to health plans, employers, and individuals.


ANN ARBOR, Mich. (PRWEB)

Workit Health, a digital healthcare company offering FDA-approved medication and evidence-based addiction treatment via web and phone apps, today announced the expansion of its board with Ben Slocum as the newest member.

Slocum’s appointment comes after Workit Health’s Series A round of funding, led by Blue Cross Blue Shield Ventures, and rapid growth of the company’s tele-MAT program in 2019. Ben Slocum brings 36 years of healthcare experience to Workit Heath’s disruptive digital solutions which offer improved outcomes for health plans, employers, and individuals at significantly lower costs than traditional systems of care.

As a former C-Suite level executive at several health plans, Ben focused on increasing consumer engagement and improving outcomes for complex health conditions. In his previous roles as CEO of WebMD Health Services, CEO of United Healthcare, Northern California, and CEO of Lovelace Health Plan he spearheaded major innovations with member experience at the forefront. He’s held leadership roles in consumer, employer, government, and provider settings.

“Ben Slocum’s experience in the healthcare industry will continue to help us expand our reach to more health plans and consumers while also prioritizing innovation and improvements for our members,” said Robin McIntosh, Workit Health’s Co-CEO. “As more health plans partner with Workit Health, we’re able to improve the lives of people struggling with addiction and ultimately to reduce the costs of the addiction epidemic nationwide.”

“On behalf of Workit Health and our current directors, I’m excited to welcome Ben to the board,” said Lisa McLaughlin, Workit Health’s Co-CEO. “2019 was a big year for us in terms of growth and partnerships, and Ben joining our team further validates Workit Health’s value to health plans, employers, and individuals.”

About Workit Health: Workit Health is a Joint Commission-accredited B-Corporation offering online, on-demand evidence-based addiction treatment including telemedicine medication for opioid and alcohol use disorders. We partner with healthcare organizations to deliver an innovative digital health solution that blends the best of human-centered design, technology, and science. Through our mobile and web apps, members meet with clinicians and counselors, join recovery groups, and complete self-set recovery goals. Our interactive curriculum of online courses keep members on track in the comfort of home. We offer 24/7 recovery that fits into daily life, designed by experts. For more information, visit http://www.workithealth.com.

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Health

Houston Attorneys Eric Pines and Stephen Goldenzweig Explain What to Do After a Brain Injury

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Eric Pines


HOUSTON (PRWEB)



Houston personal injury attorneys Eric Pines and Stephen Goldenzweig of Pines & Goldenzweig, PLLC have assisted many clients with traumatic brain injuries in Houston. When a person receives a blow to the head or a jolt to the body, they may suffer from a traumatic brain injury afterwards. These can range from mild to severe, either impacting brain cells temporarily until the injury heals, or causing bruising, tearing, bleeding, and permanent physical damage to the brain with long-term health implications.

The first priority when a traumatic brain injury occurs is to get all necessary medical care. The recovery from this type of injury can be a long one and it’s critical for patients to line up all the support they need, ranging from physicians who specialize in the treatment of brain injuries, to home healthcare, physical and occupational therapy, and counseling to help victims cope with the dramatic changes to their lives.

When a traumatic brain injury is the result of another party’s negligence, victims should seek a skilled personal injury attorney with experience handling TBI lawsuits. Eric Pines and Stephen Goldenzweig offer the following tips for anyone who has suffered a brain injury caused by someone else:

If a traumatic brain injury was the result of an assault or another criminal act, the victim should file a police report. This not only helps strengthen their case should they decide to file a lawsuit, it also helps protect the safety of others in the community.

Victims should keep all of the documentation they have about the injury. Medical records, police reports, proof of the time needed off of work, and anything else that will help make a victim’s case should be kept in a folder for easy access.

Pines and Goldenzweig also recommend that victims keep a journal where they document the impact the injury has on their day-to-day lives. It can be difficult to come up with those granular details when sitting in an attorney’s office or in a courtroom, particularly if a person’s memory has been impacted by the injury.

Finally, victims of traumatic brain injury should find a competent personal injury attorney with a proven track record of winning these cases.

A personal injury attorney will not only assist brain injury victims in proving the fault of the other party involved, but they will also help them identify the damages suffered and calculate a monetary amount for compensation.

About Pines & Goldenzweig, PLLC

Pines & Goldenzweig, PLLC is dedicated to personal injury cases. The firm’s practice areas include dog bites, car accidents, slip and fall, and traumatic brain injuries. To learn more about Pines & Goldenzweig, PLLC or to schedule a free consultation and case review, call 713-489-4410, visit http://toughinjurylawyers.com/, or stop by the firm’s office at 10101 Fondren Road, Suite 550, Houston, TX 77096.

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Technology: Computer

Q4 2019 KnowBe4 Finds Security-Related and Giveaway Phishing Email Subject Lines Get the Most Clicks

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KnowBe4 Q4 2019 Phishing Report Infographic

As identifying phishing attacks from legitimate emails becomes trickier, it’s more important than ever for end users to look for the red flags and think before they click. -Stu Sjouwerman, CEO, KnowBe4


TAMPA BAY, Fla. (PRWEB)

KnowBe4, the provider of the world’s largest security awareness training and simulated phishing platform, revealed the results of its Q4 2019 top-clicked phishing report.

The results found that simulated phishing tests with an urgent message to check a password immediately were most effective, with 39% of users falling for it. Social media messages are another area of concern when it comes to phishing. Within the same report, KnowBe4’s top-clicked social media email subjects reveal that LinkedIn messages are the most popular at 55%, followed by Facebook at 28%.

“With more end users becoming security-minded, it’s easy to see how they fall for phishing scams related to changing or checking their passwords,” said Stu Sjouwerman, CEO, KnowBe4. “They should be especially cautious if an email seems to good to be true, such as a giveaway. As identifying phishing attacks from legitimate emails becomes trickier, it’s more important than ever for end users to look for the red flags and think before they click.”

In Q4 2019, KnowBe4 examined tens of thousands of email subject lines from simulated phishing tests. The organization also reviewed ‘in-the-wild’ email subject lines that show actual emails users received and reported to their IT departments as suspicious. The results are below.

Top 10 General Email Subjects

  •     Change of Password Required Immediately 26%

  •     Microsoft/Office 365: De-activation of Email in Process 14%

  •     Password Check Required Immediately 13%

  •     HR: Employees Raises 8%

  •     Dropbox: Document Shared With You 8%

  •     IT: Scheduled Server Maintenance – No Internet Access 7%

  •     Office 365: Change Your Password Immediately 6%

  •     Avertissement des RH au sujet de l’usage des ordinateurs personnels 6%

  •     Airbnb: New device login 6%

  •     Slack: Password Reset for Account 6%

*Capitalization and spelling are as they were in the phishing test subject line.

**Email subject lines are a combination of both simulated phishing templates created by KnowBe4 for clients, and custom tests designed by KnowBe4 customers.

When investigating ‘in-the-wild’ email subject lines, KnowBe4 found the most common throughout Q4 2019 included:

  •     SharePoint: Approaching SharePoint Site Storage Limit

  •     Microsoft: Anderson Hauck has shared a Whiteboard with you

  •     Office 365: Medium-severity alert: Unusual volume of file deletion

  •     FedEx: Correct address needed for your package delivery on [[current_date_0]]

  •     USPS: Your digital receipt is ready

  •     Twitter: Your Twitter account has been locked

  •     Google: Please Complete the Required Steps

  •     Cash App: Your Account Has Been Closed

  •     Coinbase: Important Please Resolve Error Now

  •     Would you mind taking a look at this invoice?

*Capitalization and spelling are as they were in the phishing test subject line.

**In-the-wild email subject lines represent actual emails users received and reported to their IT departments as suspicious. They are not simulated phishing test emails.

For more information on KnowBe4, visit http://www.knowbe4.com.

About KnowBe4

KnowBe4, the provider of the world’s largest security awareness training and simulated phishing platform, is used by more than 30,000 organizations around the globe. Founded by IT and data security specialist Stu Sjouwerman, KnowBe4 helps organizations address the human element of security by raising awareness about ransomware, CEO fraud and other social engineering tactics through a new-school approach to awareness training on security. Kevin Mitnick, an internationally recognized cybersecurity specialist and KnowBe4’s Chief Hacking Officer, helped design the KnowBe4 training based on his well-documented social engineering tactics. Tens of thousands of organizations rely on KnowBe4 to mobilize their end users as the last line of defense.

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Industry: Healthcare

Seniors Helping Seniors® Identifies Gap in Senior Care Segment – Clients are Asking for More, as Record Number of Seniors Age in Home

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READING, Pa. (PRWEB)

Since its foundation in 1998, Seniors Helping Seniors® has focused on the delivery of a superior customer experience through its in-home senior care program. Yet, the leadership found the deliverables limiting – both to their end customer and their franchisees.

“Our clients have always celebrated the relationship with our company. However, they have also asked for more,” said Kiran Yocom, founder. “We were tired of having to say no to their needs, yet, we needed to ensure operational excellence before delivering a new level of service to them.”

Yocom, along with the leadership of the 200+ unit brand that employs active seniors to help their fellow seniors age in place, worked tirelessly to create a full-service offering branded 360°.

“There is no better term to describe it,” said Philip Yocom, CEO. “360° is all encompassing. No matter who we ask what does 360 mean to them – the answers are similar – holistic, full-circle, all encompassing. Blended with our operational standards, we are confident this new program will help us stand out not only to our customers, but our franchise owners.”

The leadership team also emphasized the value of community and highlighted how Seniors Helping Seniors® is not just about helping individuals, but helping entire families by providing peace of mind to family members who worry about their loved ones. Thanks to Seniors Helping Seniors®, they can take comfort in knowing their loved ones are receiving supportive and loving care.

“To me, 360° means putting seniors and their families first and providing unique care through a uniquely caring community,” said Howard Algeo, Seniors Helping Seniors® Director of Business Development and Training.

For Seniors Helping Seniors®, a 360° view also means emphasizing the importance of teamwork among leadership, franchise owners and caregivers. When all parties work together, seniors and families benefit tremendously. What’s more, leadership, franchise owners and caregivers feel good about the brand and knowing they are all part of a larger mission.

“360° means taking an all-encompassing look at the business and realizing that when you provide warm, compassionate care, everybody benefits,” Seniors Helping Seniors® Vice President of Operations Daniel Jan said. “We are all in this together as a team and we can provide it all for our receivers.”

Franchise owners will offer a full circle of care, with a focus on warm, compassionate care every day, every hour, every second and at every level. With 360°, Seniors Helping Seniors® franchise owners and the seniors they employ are setting the stage for a loving and compassionate relationship with those who receive their care.

“The 360° rollout will include scale – ensuring franchise owners are ready and equipped to deliver excellence to our customers,” said Glenn Leingang, Director of Franchise Development. “ “Having a 360° view at Seniors Helping Seniors® means possessing a true desire to find franchise owner candidates who are mission-oriented and have the capacity and drive to obtain exceptional results.”

Randy and Judy Loubier, franchise owners in New Hampshire have been pioneering Seniors Helping Seniors 360® for the brand and noted the meaning of the concept as, “Completing the Circle of Care”.

“To me, 360° means to truly complete the circle of care by taking care of aging adults who desire top quality care, loving kindness and encircling them with an ability to address each need from day one to the end of life,” Judy Loubier said. “These people desire and deserve to be surrounded by caregivers who have become part of the family, who love them, and who can step up as the need arises in order to provide medications, bed baths, transfers, all from a place in our hearts that got this started in the first place. 360° gives us the opportunity, it gives us a voice, and it speaks to the vision.”

Seniors Helping Seniors® was founded in 1998 when husband-and-wife team Philip and Kiran Yocom decided to open a business that would provide loving and compassionate in-home care to seniors. Kiran, who grew up in India, was inspired by Mother Teresa and the work she was doing in the country. After years of donating her weekly allowance to The Sisters of Charity, Kiran became a follower of the Catholic nun and worked alongside her to help with humanitarian efforts. This work solidified Kiran’s belief in providing loving and empathetic care to seniors and provided the foundation for Seniors Helping Seniors®. Kiran moved to the U.S. in 1995 and married Philip shortly after that. In 1998, the Yocoms founded Seniors Helping Seniors® in Reading, Pennsylvania as a non-profit. In 2006, the Yocoms decided to leverage Philip’s franchising experience and opened the business for franchising.

Seniors Helping Seniors® stands out in a crowded senior care industry by focusing on the practice of employing active seniors to provide services to their less active counterparts, referred to as receivers. Caregivers help receivers take care of the day-to-day tasks that become more challenging with age while also earning supplemental income. Both are carefully matched based on the receiver’s specific needs, as well as personality and preferences. What’s more, Seniors Helping Seniors® emphasizes building a deep and long-lasting relationship between caregivers and receivers.

“At Seniors Helping Seniors®, we put love at the center of everything we do,” Kiran said. “We truly believe in The Power of Love® and Bringing Love into the lives of Seniors with Dignity and Respect®. In order to get to that stage of love, though, everything must begin with warmth. We want to emphasize that heartfelt and compassionate care to our franchise owners.”

The brand started franchising in 2006 and has since grown to over 200 locations in more than 30 states, plus seven international locations. Seniors Helping Seniors® is continuing to expand its footprint across the U.S. and the globe and welcomes conversations with prospective franchisees who have high business acumen and want to give seniors The Gift of Independence®.

ABOUT SENIORS HELPING SENIORS®

Seniors Helping Seniors® was founded by husband-and-wife duo Kiran and Philip Yocom. Kiran, who grew up in India and later worked to advance humanitarian efforts alongside Mother Teresa. After moving to the U.S. in 1995 and marrying her husband Philip, the Yocoms felt called to provide loving care to seniors and to cultivate an exchange of gifts at every generational level. Together, the Yocoms founded Seniors Helping Seniors® in 1998, opening the brand up to franchising in 2006. With a mission to be the most respected and rewarding homecare provider in the U.S., Seniors Helping Seniors® stands apart from as the only company that prioritizes hiring active seniors to provide care services to their less-active counterparts. Seniors Helping Seniors® aligns caregivers and care recipients based on the abilities and needs of both by offering a wide range of care services. Seniors Helping Seniors® has grown to over 200 locations in 30-plus states and seven international locations, with 125 franchise partners. For more information on Seniors Helping Seniors®, visit https://seniorshelpingseniors.com/. To learn more about franchising opportunities with Seniors Helping Seniors®, please visit https://franchise.seniorshelpingseniors.com/.

Health: Mental Health

MBX Awarded Best Personal Training Studio in Suburban Essex Magazine’s Best of Essex 2019 Reader’s Choice Awards

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“I have dedicated many years to developing a program that can truly change and improve people’s lives. I am beyond thrilled to be nominated and recognized for all the hard work I’ve poured my heart and soul into!”


MONTCLAIR, N.J. (PRWEB)

Suburban Essex Magazine announced the 2019 Best of Essex nominees at the beginning of July 2019. This contest is open to business owners in New Jersey and seeks to promote quality local businesses throughout Essex county.

Among the nominees was MBX, a woman-owned fitness studio located in Montclair, New Jersey. After launching the studio in 2017, MBX landed its very first “Best of Essex” nomination and win as part of Suburban Essex Magazine’s Annual Reader’s Choice Awards.

The founder of MBX, Thelis Negron, was ecstatic about the announcement saying, “I have dedicated many years to developing a program that can truly change and improve people’s lives. I am beyond thrilled to be nominated and recognized for all the hard work I’ve poured my heart and soul into!”

While this is the fitness studio’s first win, Thelis is no stranger to success. Over the last 15 years, Thelis has cultivated a successful career as a personal trainer having trained with high-end clientele during her time in Hollywood, California. Thelis has also been featured on weight-loss reality shows and fitness magazines like Shape and Women’s Health.

MBX is best known for its 12 Week Program (https://www.mbxfit.com/program/) a revolutionary system developed by Thelis to maximize physical and mental health. Along with several certifications in personal training and nutrition, Thelis holds a Master’s degree in mental health. Drawing from her unique combination of education, experience and industry knowledge, Thelis has developed a sophisticated fitness program that is proving popular with Montclair residents. Additionally, MBX is the only personal training studio in Montclair, New Jersey offering private personal training to its clientele.

Thelis was quick to clarify that MBX does not promote “fad diets”. She elaborated that the program is, instead, built to help clients progressively develop a healthier lifestyle that can help them maintain a healthy weight for life. More importantly, Thelis emphasized how the program incorporates mind training techniques that promote mental wellness alongside physical fitness.

MBX and the rest of the Best of Essex 2019 winners are featured in Suburban Essex Magazine’s Winter 2019 issue (https://issuu.com/vicinity/docs/essex_1219se/52).

About MBX Personal Fitness Studio

MBX – The Mind & Body Experience is Montclair’s premier high-end personal training and nutrition studio. The studio was founded by Thelis Negron, a veteran personal trainer with over 15 years of experience in the health & wellness industry.

About Thelis Negron

Thelis Negron, founder of MBX, is a mental health professional with a Bachelor’s degree in Sociology from Haverford College, a Mental Health Master’s degree from UMass, certifications from the National Academy of Sports Medicine (NASM), the top ranked school for personal training, nutrition and physical therapy in the country. Thelis is also a certified Life Coach through an ICF accredited institution. She began her personal training career in Hollywood, CA where she worked with a high-end clientele inclusive of celebrities, was on several weight-loss reality shows and was featured in popular fitness magazines. She has now been personal training for 15 years has drawn from her experience as a mental health professional and combined it with her skills as a certified Life Coach to develop a unique mind training technique she has coined “Mind Coaching.” Thelis speaks four languages and has lived and traveled all over the world from Europe, to South America, Africa, Asia and has also lived in several major cities in the U.S. including Philadelphia, Manhattan, Los Angeles, and was residing in Montclair, NJ for 6 years when she opened MBX.

https://www.mbxfit.com

info@mbxfit.com

1 Bellevue Plaza Ste. 6

Montclair, New Jersey 07043

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Business: Insurance

PGU enhances client experience with the launch of the PGU Employer Resource Center

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PGU and Enquiron Logos

PGU | Enquiron

We feel strongly that partnering with Enquiron will provide our policyholders with the tools and knowledge they need to make informed decisions that mitigate the risk of costly litigation.


BOSTON (PRWEB)

“Our public entity clients face a challenging and constantly evolving environment when it comes to employment practices liability. We feel strongly that partnering with Enquiron will provide our policyholders with the tools and knowledge they need to make informed decisions that mitigate the risk of costly litigation,” said Marty Kanipe, President of Professional Governmental Underwriters.

Enrolled PGU policyholders will have unlimited access to a variety of content, tools and resources, including employment law advice, essential to running a business.

“We are excited to partner with PGU and deliver the PGU Employer Resource Center to their policyholders,” said Mike Naclerio, President and CEO of Enquiron. “By bringing these resources to the PGU portfolio, we are able to help policyholders focus on making their organizations successful, while simultaneously helping PGU grow and expand their business.”

ABOUT PGU:

Professional Governmental Underwriters, Inc. is a full-service risk management company dedicated to assisting public, educational and non-profit entities in the management of their professional liability exposures. Current operations are dedicated to underwriting and marketing Public Officials Liability, Law Enforcement Liability and Educators Liability insurance. We provide state-of-the-art professional underwriting management and loss control advisory services on behalf of our designated carriers.

ABOUT ENQUIRON

Enquiron, http://www.enquiron.com, headquartered in Boston, Massachusetts, provides consultative business solutions to employers in all 50 states, across various industries, sectors and sizes. Since 1996, Enquiron has revolutionized the way that services impacting Human Resources, Employment Law, Healthcare, Retirement, Cyber Security and more are delivered to and utilized by employers. Enquiron has locations across the United States and is a trusted partner to organizations who need specific answers to specific questions. https://www.linkedin.com/company/enquiron

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Business: Executives

Kane Russell Coleman Logan Appoints Jeff Novel to Managing Director of Administration

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Going forward, the Board of Directors will set the strategic direction for the firm and, as Managing Director of Administration, I will coordinate with our C-suite on how to best implement the right initiatives to achieve our goals.


DALLAS (PRWEB)

Kane Russell Coleman Logan has named Jeff Novel as the Managing Director of Administration. The firm recently announced a change in leadership, including the switch to a C-suite business management model.

Novel, a litigation attorney and Director, has been with KRCL for over 15 years. In his new role, Novel will work closely with the firm’s team of professional business managers.

Novel said that “Going forward, the Board of Directors will set the strategic direction for the firm and, as Managing Director of Administration, I will coordinate with our C-suite on how to best implement the right initiatives to achieve our goals. With our vision for the future of the firm, working together as a cohesive team is vital for our success.”

KRCL’s C-suite consists of Chief Executive Officer Business Operations Mike Demarest, Chief Financial Officer Nathan Benson, Chief Marketing Officer Christine Harris, Chief Talent Officer Pamela Worthington and Chief Information Officer Greg Amme.

“We are excited to embark on the legacy plan set forth by the firm’s founders,” Managing Director Karen Cox said. “Jeff is a great attorney and his tenure with the firm helps ensure that we stay anchored to the firm’s mission and core values.”

Kane Russell Coleman Logan is a full-service law firm with offices in Dallas and Houston. Formed in 1992 with five lawyers, today KRCL employs nearly 75 attorneys. The Firm provides professional services for clients ranging from Fortune 500 companies to medium-sized public and private companies to entrepreneurs. KRCL handles transactional, litigation and bankruptcy matters in Texas and throughout the country.

SOURCE: Kane Russell Coleman Logan PC

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Health

RoviSys Relocates to Thousand Oaks, CA & Expands To Accommodate Growth

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We are excited to expand operations in Southern California. Our thirty years of experience and exceptional service distinctly qualifies RoviSys to deliver solutions that improve operational and financial results for our customers.


AURORA, Ohio (PRWEB)

RoviSys, a leading independent provider of comprehensive process automation, systems integration, and building management solutions, announced today the continued expansion of operations in California, with a new office in Thousand Oaks. Since 2015, RoviSys & RoviSys Building Technologies have supported customers and developed new relationships with clients across Southern California. The Thousand Oaks office represents a lasting commitment to the local community, providing space for forty existing engineers, managers and support staff, and ample space for growth.

“Our expansion in Thousand Oaks reflects a strategic decision to strengthen presence throughout the Western United States, and cater to customers who have worked or are working with RoviSys, but prefer a partner with a regional location,” said John Robertson, CEO. “We are excited to expand operations in Southern California. Our thirty years of experience and exceptional service distinctly qualifies RoviSys to deliver solutions that improve operational and financial results for our customers.”

RoviSys provides industrial network, control systems integration, MES, and industrial AI solutions across many industries including Life Sciences, Water Resources, Consumer Goods, Oil & Gas, & Chemical through professional partnerships and a commitment to vendor independence. The company has locations across North America, and internationally, with offices in Singapore, Taiwan, and the Netherlands. An ever-growing team of employees with experience and knowledge to are committed to improving productivity and quality in the age of digital transformation.

“RoviSys chose to open its newest office in Thousand Oaks because of the city’s location, potential for attracting talent, and recognition as a center of innovation and technology” said Matt Knott, Director – Life Sciences. “Our focus on technologies for pharmaceutical and biotech companies will be well received in the economy here.”

About RoviSys

The RoviSys Company is a leading independent provider of information management solutions, manufacturing automation solutions, control systems integration, building automation, and enterprise and industrial networks. Since 1989, we have built a reputation of quality and continuity, technical expertise, and attentive customer service. We are distinctly qualified to deliver solutions that drive productivity, improve product quality, increase asset utilization and integrate technology for the Chemical, Petrochemical, Life Science, Consumer Packaged Goods, Glass, Metals, Power & Energy, Data Center, Building Management, Water & Wastewater, Paper & Wood and Oil & Gas industries.

For more information visit http://www.rovisys.com.

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Science: Biology

Life Molecular Imaging announces presentation of new scientific data at the Human Amyloid Imaging Meeting

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Life Molecular Imaging at the 14th Human Amyloid Imaging meeting in Miami

Exciting new research presented using Life Molecular Imaging compounds at the 14th Human Amyloid Imaging meeting in Miami, Florida


BERLIN (PRWEB)

Life Molecular Imaging (LMI) announces today that new research results on its approved and investigational positron emission tomography (PET) neuroimaging tracers will be presented at the 14th Human Amyloid Imaging (HAI) meeting in Miami (January 15-17, 2020). The contributions cover nine (9) presentations demonstrating the value of its approved compound Neuraceq™ (florbetaben F18 injection), and fifteen (15) presentations supporting the potential of its investigational Tau-PET tracer PI-2620.

A comprehensive clinical evaluation with imaging biomarkers, such as amyloid PET imaging, can improve the diagnostic accuracy. In addition, the combination of Neuraceq™ and the investigational PI-2620 tracer for the detection of tau pathology, provides a powerful PET imaging biomarker platform for the appropriate characterization of subjects enrolled in clinical trials supporting drug development in neurodegenerative diseases. The value of imaging biomarkers, particularly the combination of amyloid-beta and tau in the same subjects, is increasingly recognized. Highlights also include the presentation of the results from a multi-center evaluation of PI-2620 in subjects with progressive supranuclear palsy (PSP) as well as a poster describing the performance of PI-2620 in subjects with corticobasal syndrome (CBS).

“We are particullary impressed by the data that the research groups collected over the last year in PSP patients” said Dr. Andrew Stephens, MD, PhD, CMO of Life Molecular Imaging. “PI-2620’s ability to also detect 4R tauopathies, such as PSP and CBS allows us to pursue the development of PI-2620 not only for AD, but also for additional neurodegenerative diseases, where previous tau tracers showed limitations.”

Datasets involving LMI compounds presented at the HAI meeting include the following presentations:

Amyloid-PET Neuroimaging presentations involving Neuraceq (florbetaben F18 injection):

January 15, 2020

  • Bullich et al. (Poster #5 Session 1A): Early detection of amyloid load using 18F-Florbetaben PET

  • Klein et al. (Poster #21 Session 1A): Concordance of visual and quantitative assessments of baseline amyloid scans in the GRADUATE gantenerumab studies

  • Landau et al. (Poster #24 Session 1A): Validation of highly sensitive and specific florbetaben positivity thresholds using ADNI participants and young controls

  • Lao et al. (Poster #25 Session 1A): Additive contribution of white matter hyperintensity to amyloid and neurodegeneration on cognitive decline in a diverse, community-based cohort of older adults

January 16, 2020

  • Gispert et al. (Poster #84 Session 2A): Preliminary quantitative results of the AMYPAD prognostic and natural history study

  • Seo et al. (Poster #88 Session 2A): Head-to-head comparison of F-Florbetaben and F-Flutemetamol uptakes in the cortex, striatum and white matter

  • Ewers et al. (Poster #69 Session 2A): Higher microglia biomarker levels are associated with slower rates of amyloid-beta accumulation in humans and in a transgenic mouse model of amyloid-beta

  • Kim et al. (Poster #91 Session 2A): Prevalence of amyloid PET positivity in cognitively normal East Asian populations

January 17, 2020

  • Iaccarino et al. (Poster #137 Session 3A): In vivo amyloid-PET and tau-PET evidence in early-onset Alzheimer’s Disease: taking the LEADS

Tau-PET Neuroimaging presentations involving PI-2620:

January 15, 2020

  • Bischof et al. (Poster #4 Session 1A): A pons cluster detected by a data-driven approach may serve as a favorable reference region for 18F-PI-2620 Tau PET analysis

  • Stevenson et al. (Poster #48 Session 1A): Monitoring disease pathophysiology using multiparametric PET acquisitions: The McGill TRIAD Cohort

January 16, 2020

  • Aguero et al. (Session 3: Neuropathology I): Comparison of autoradiographic binding profiles of Flortaucipir, MK-6240 and PI-2620 in human postmortem tissue samples across the spectrum of neurodegenerative diseases

  • Malarte et al. (Session 4: Neuropathology II): In vitro characterization of second-generation tau pet tracers in human autopsy brain tissue

  • Brendel et al. (Session 5: Clinical I): 18F-PI-2620 tau-PET in Progressive Supranuclear Palsy – A multi-center evaluation

  • Stephens et al. (Poster #90 Session 2A): PI-2620 Tau PET is associated with amyloid-beta levels in scans from subjects of the elenbecestat MissionAD program

  • Villemagne et al. (Poster #76 Session 2A): Assessing Aβ, tau, and reactive astrocytosis in aging and AD

January 17, 2020

  • Brendel et al. (Poster #122 Session 3A): Perfusion-phase 18F-PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

  • Brendel et al. (Poster #123 Session 3A): Binding characteristics of 18F-PI-2620 differentiate the clinically predicted tau isoform in suspected 3/4-repeat and 4-repeat tauopathies

  • Brendel et al. (Poster #124 Session 3A): 18F-PI-2620 tau-PET for assessment of heterogeneous neuropathology in corticobasal syndrome

  • Bullich et al. (Poster #125 Session 3A): Optimal reference region for the quantification of tau load in the brain using 18F-PI-2620 PET

  • Koran et al. (Poster #143 Session 3A): Validation of clinical protocols for clinicians analyzing 18F-PI-2620 tau PET/MRI images

  • Dore et al. (Session 7: Tau I): Towards a CenTauR cortical mask

  • Toueg et al. (Poster #169 Session 3A): Elevated medial temporal lobe Tau PET with 18F-PI2620 in normal controls with “borderline” neuropsychological testing profiles

  • Trelle et al. (Poster #170 Session 3A): Hippocampal tau accumulation predicts individual differences in episodic memory in cognitively normal older adults

About Neuraceq (florbetaben F18 injection)

Indication

Neuraceq™ (florbetaben F18 injection) is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer’s Disease (AD) and other causes of cognitive decline.

A negative Neuraceq scan indicates sparse to no amyloid neuritic plaques and is inconsistent with a neuropathological diagnosis of AD at the time of image acquisition; a negative scan result reduces the likelihood that a patient’s cognitive impairment is due to AD. A positive Neuraceq scan indicates moderate to frequent amyloid neuritic plaques; neuropathological examination has shown this amount of amyloid neuritic plaque is present in patients with AD, but may also be present in patients with other types of neurologic conditions as well as older people with normal cognition.

Neuraceq™ is an adjunct to other diagnostic evaluations.

Limitations of Use

  • A positive Neuraceq™ scan does not establish the diagnosis of AD or any other cognitive disorder.

  • Safety and effectiveness of Neuraceq™ have not been established for (i) Predicting development of dementia or other neurologic conditions; (ii) Monitoring responses to therapies.

Important Safety Information

Risk for Image Interpretation and Other Errors

Neuraceq can be used to estimate the density of β-amyloid neuritic plaque deposition in the brain. Neuraceq is an adjunct to other diagnostic evaluations. Neuraceq images should be interpreted independent of a patient’s clinical information. Physicians should receive training prior to interpretation of Neuraceq images. Following training, image reading errors (especially false positives) may still occur. Additional interpretation errors may occur due to, but not limited to, motion artifacts or extensive brain atrophy.

Radiation Risk

Administration of Neuraceq, similar to other radiopharmaceuticals, contributes to a patient´s overall long-term cumulative radiation exposure. Long-term cumulative radiation exposure is associated with an increased risk of cancer. It is important to ensure safe handling to protect patients and health care workers from unintentional radiation exposure.

Most Common Adverse Reactions

In clinical trials, the most frequently observed adverse drug reactions in 872 subjects with 1090 Neuraceq™ administrations were injection/application site erythema (1.7%), injection site irritation (1.1%), and injection site pain (3.4%).

About PI-2620

Tau deposits, in conjunction with beta-amyloid plaques, represent the other pathological hallmark of Alzheimer’s disease, with tau deposits further playing an important role in other neurodegenerative diseases. PI-2620 is binding to 3R/4R and 4R tau deposits and is a next generation 18F-labeled investigational PET tracer with favourable properties and imaging characteristics. It was discovered in a research collaboration between Life Molecular Imaging and AC Immune, a Swiss-based clinical stage biopharmaceutical company. Life Molecular Imaging has the exclusive, world-wide license for research, development and commercialization of tau PET tracers generated within the discovery program.

About Life Molecular Imaging (LMI)

Life Molecular Imaging (LMI, formerly Piramal Imaging) was formed in 2012 with the acquisition of the molecular imaging research and development portfolio of Bayer Pharma AG. It is now part of the Alliance Medical Group (a member of the Life Healthcare Group) offering an integrated business including research and development laboratories, a network of cyclotrons, radiopharmacies and imaging facilities. By developing novel PET tracers for molecular imaging, LMI is focusing on a key field of modern medicine. The organization strives to be a leader in the Molecular Imaging field by developing innovative products that improve early detection and characterization of chronic and life-threatening diseases, leading to better therapeutic outcomes and improved quality of life.

Please visit https://life-mi.com.

About Life Healthcare Group

Life Healthcare Group is a market-leading, international, diversified healthcare organization. Life Healthcare has over 33 years’ experience in the South African private healthcare sector, and currently operates 66 healthcare facilities in southern Africa. Services include acute hospital care, acute physical rehabilitation, acute mental healthcare, renal dialysis, and employee health and wellness services. The Group owns Alliance Medical Group, the leading independent provider of medical imaging services within Europe, operating across 10 international countries. Life Healthcare also owns Scanmed S.A. (Poland) which provides healthcare and medical services in 20 Polish cities, with over 65 medical specialisations and diagnostic services available in 32 facilities. Visit lifehealthcare.co.za

Media Contact:

Nicole Fletcher | Marketing Communications | Life Molecular Imaging

+1 857-202-1122 | n.fletcher@life-mi.com

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Technology: Electronics

New Stadium Listening Solution by Broadcastvision Entertainment

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LONGMONT, Colo. (PRWEB)

This new solution from Broadcastvision Entertainment – http://www.broadcastvision.com – allows thousands of listeners to hear live local audio on their smartphone or tablet using the AudioFetch app. It’s ideal for attendees with hearing disabilities or simply those that want to clearly hear the main event over hollering vendors, cheering fans, blaring vuvuzelas and other miscellaneous event din. Any venue that draws a large crowd–sports stadiums, concert arenas, large auditoriums, indoor or outdoor amphitheaters–can use this new audio streaming solution to provide hearing assistance for attendees.

When AudioFetch was first developed, the focus was on smaller venues and smaller crowds but as the company has grown, so have the crowd sizes that want to listen. The interest from stadiums and large arenas around the world required a solution for mass listening.

For the stadium or event venue, it works similarly to our other local audio streaming products. Just three easy steps get you up and running: 1. Connect the audio source(s) to AudioFetch using the included cables; 2. Connect the AudioFetch to the WiFi router; and 3. Attendees download the AudioFetch App and listen in real-time. (And if you want to get technical, that’s really only two steps on you!)

For attendees, it’s the exact same process as any other venue. Simply download the AudioFetch App for Apple or Android, connect to the local WiFi and start listening!

Broadcastvision is your trusted manufacturer for high quality commercial grade entertainment products including AudioFetch (TV audio to Apple and Android smartphones), CAB for cable, satellite and IPTV set top box control, Axcess Universal Personal Screen Controller, 863MHz / 900MHz Wireless, FM Wireless, Large Screen TVs and Mounts, Sound Systems, Digital Signage, Branded Music and Messaging and Personal Viewing Screens.

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