Nitric Oxide Functional Chewing Gums, promoting a nitric oxide favorable oral microbiome

Systemic vascular health is greatly influenced by our oral health and a functional prebiotic nitrate chewing gum may provide a consumer-friendly means that optimizes a nitric oxide favorable oral microbiome.

ROCKVILLE, Md. (PRWEB)
March 23, 2023

MyFitStrip’s first generation functional chewing gums are designed to both increase the alkalinity of saliva and shift the oral microbiome towards a nitric oxide favorable microbiota for converting dietary nitrate from heart healthy plant-based foods.

Oral and systemic wellness share many common risk factors, including nitric oxide deficiency. Today, many oral health products ranging from toothpastes to mouthwashes indiscriminately eliminate the bacteria in the mouth. Studies have repeatedly shown that dysregulation of the oral microbial community is associated with poor oral and cardiovascular health. A critical step in restoring oral and systemic health is dependent upon a functional oral microbiome capable of converting dietary nitrate to nitric oxide.

Dietary inorganic nitrates, present in leafy greens, celery, and beets, are converted to nitric oxide beginning with oral bacteria found on the tongue. “If these nitric oxide-promoting bacteria are diminished by poor dietary lifestyle choices or from excessive use of harsh mouthwashes, nitric oxide-beneficial outcomes, in particular, vascular and oral health, can be blunted,” according to Dr. Shawn J. Green, founder of MyFitStrip. Green published some of the earliest work on the role of nitric oxide in innate or natural immune function and was the founder of Berkeley Test and inventor of the clinically supported nitric oxide supplement, Berkeley Life Professional, and the co-inventor of the next generation, clinically validated nitric oxide nutraceutical, Vascanox.

MyFitStrip observed that chewing slow-release functional chewing gums developed by Per Os Biosciences infused with a patent-pending formula of inorganic prebiotic nitrate and ascorbate shifts the oral microbiome towards a nitric oxide favorable microbiota. As important, the nitric oxide chewing gum also diminishes bacteria often associated with poor oral and systemic wellness. “Chewing the gum for several minutes throughout the day appears to increase the residence time of the prebiotic actives in the oral cavity thereby promoting a healthy microbiome balance within the matter of several hours”, Green continues, “What was most striking from these initial observations was the acute improvement and expeditious nature of this favorable microbiome shift.”

Aside from enhancing nitric oxide-promoting bacteria, several investigators have reported that salivary nitrate lowers the incidence of tooth decay and gum inflammation. Using MyFitStrip’s Saliva Testing Strips and Bristle Oral Health microbiome testing platform, early results are showing an increase in local nitric oxide and salivary alkalinity, plus a favorable shift in the oral cavity towards nitric oxide-promoting bacteria. A corresponding decrease in bacteria-associated with poor health outcomes was apparent within hours of chewing MyFitStrip Bioactive Nitric Oxide Chewing Gum intermittently throughout the day. Observations will be published later this year and follow-on studies are underway to further evaluate the oral and systemic health connection in the context of oral nitric oxide bioavailability. This first-generation chewing gum is not intended to replace a heart healthy serving of a nitrate-rich leafy green-beet salad or clinically-validated dietary supplement, but simply to enhance a microflora that favors nitrate bioconversion in the oral cavity, a critical first step in nitric oxide formation.

“Systemic health is greatly influenced by our oral health”, Green continues, “aside from our dietary choices, these functional prebiotic chewing gums may provide a consumer-friendly means that optimizes a nitric oxide favorable oral microbiome. In doing so, our functional gums may emerge to be helpful in complementing plant-based dietary sources to sustain oral and cardiovascular wellness. If so, such a simple delivery platform as gum would be helpful to those with limited access to oral hygiene products.”

Clinical evidence from the Karolinska Institutet, University of Exeter, William Harvey Research Institute, Queen Mary University, Oral Microbiome Research Group of the Foundation for the Promotion of Health and Biomedical Research of Valencia, University of Minnesota, among other notable biomedical research centers and universities continue to reinforce the importance of dietary nitrate’s role in improving oral and systemic health.

About

MyFitStrip believe wellness is highly personal. Each individual converts natural food derived bioactives, uniquely. By providing easy to use, affordable, non-invasive saliva test strip and targeted functional dietary solutions, MyFitStrip users can make informed real-time dietary choices. We change lifestyles one self-test and one healthy choice at a time. MyFitStrip is a behavior-driven, science supported approach to wellness. We are committed to shifting society’s current practice of managing chronic conditions to preventing these conditions. Our initial focus is to ensure optimal nitric oxide, a natural molecule vital to life, while taming an underappreciated inflammatory trigger, uric acid.

For more information about MyFitStrip’s self care testing solutions and designing dietary wellness formulas contact us at info@myfitstrip.com

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