All posts by imreal

Animal Health: A Promising Market with Rapid Growth


China’s animal health market reached 4 billion euros (or 1 billion RMB) in 2017, and is expected to reach 9 billion euros (or 70 billion RMB) in the next seven years.

2019 Echemi Animal Health Industry Analysis Forum, organized by Echemi and VNU Exhibitions Europe, was held at Hall S3, Qingdao Cosmopolitan Exposition. Currently, related enterprises are benefited a lot from the rapid growth of the animal health industry and great market demand home and abroad. Following the market trend, Echemi focuses on the animal health industry to explore potential value. It is the fifth industrial forum organized by Echemi. During the forum, David Zhang, the founder of Echemi, and experts from China, Bangladesh, Vietnam, Ukraine and Argentina were invited to share the development trend of the animal health industry with more than 20 global buyers and over 70 Chinese suppliers. By doing so, Echemi and the global partners will know more about the market demand and seek a win-win scenario.

At 9:30 a.m., David Zhang firstly made an opening speech, showing the warmest welcome to all the distinguished guests. And then, he made an in-depth analysis of the animal health market.

“Through years of development, the global animal health market has entered a period of stability. In addition to the negative growth in 2009 due to the global financial crisis, the animal health market has maintained a steady growth. The market size increased from $13.7 billion in 2004 to $31.9 billion in 2018, with a compound annual growth rate of 5.7%.

The market size of China’s animal health industry still lags far behind world leading countries. However, with the gradual attention paid by the country to animal epidemic prevention and control and food safety, the domestic animal health industry has developed rapidly and maintained a relatively upward trend. China’s animal health market reached 4 billion euros (or 1 billion RMB) in 2017, and is expected to reach 9 billion euros (or 70 billion RMB) in the next seven years.” David Zhang said on the opening ceremony.

Professor Zou Ming from Qingdao Agricultural University delivered a speech entitled Market of Animal Health Industry & Research of New Veterinary Drug. In his speech, Professor Zou introduced current research situation of domestic and foreign animal health market, and research status of new veterinary drugs in China and beyond. He pointed out, “In the past 10 years, the veterinary drug industry has gradually formed an industrial system with complete categories, diverse varieties, advanced technology, complete industrial chain. API and some pharmaceutical products have international competitiveness.”

Mr. Mohammad Shaheen Shah gave a detailed analysis about the feed market in Bangladesh. Taking the market demand, livestock population and products in Bangladesh as examples, Mr. Mohammad Shaheen Shah stated that, the trends of feed additive were shifting meat & bone meal (MBM) to alternative protein and shifting antibiotic to antibiotic substitute. Besides, feed miller were looking for antibiotic substitutes such as organic acids, phytobiotics, prebiotic, probiotic, symbiotics, immune stimulants, sssential oils, and herbal extracts.

Mr. Nguyen Viet Anh analyzed the animal market in Vietnam. From the perspective of the feed market in Vietnam, Mr. Nguyen Viet Anh introduced the character of and challenges facing with the husbandry market in Vietnam, pointing out that the industry was shifting into intensification. In 2014, the government promulgated the livestock restructuring plan, which aimed to restructure livestock production, envisage changes in the livestock population’s spatial distribution, in farming systems, and in value chains, along with institutional strengthening. Currently, there are 66 companies meeting GMP standard, producing and distributing with 6,768 medicines on the list of veterinary drugs permitted for circulation and more than 3,000 medicines of 40 importing countries.

Dr. Fedir Marchenkov delivered a speech entitled Ukraine Feed Market Analysis. In his speech, Dr. Fedir Marchenkov introduced the feed market in Ukraine, main problems for livestock, and products trend. In terms of beef export in Ukraine, he pointed out that “Ukraine has been successful in developing export markets for their cattle in Central Asia, Caspian Sea countries, and North Africa. There will be no significant export destination changes are expected in 2019.” However, the Africa swine fever, infectious diseases and contamination in feed are tough issues that the global husbandry industry needs to deal with.

Finally, Ms. Eugenia Campanelli took the pet food market in Argentina as an example to introduce the feed industry in Latin America. She pointed out that in 2018, 720 million tons of animal feed was produced around the world, and Latin America and the Caribbean were responsible for 120 million tons, representing 17% of global production. Latin America and the Caribbean are important producers, consumers and exporters of grains and cereals, pork, poultry, cattle, and aquatic products. The region is the leader of the animal industry.

At 1:00 p.m., Echemi guided tour began. Buyers were divided into two groups to visit Hall S2 for feed products and Hall S3 for animal health products respectively according to their demands, and exchanged product information with many exhibitors on site. Through this activity, overseas buyers can get more information about Chinese suppliers, and in return, suppliers can also use this opportunity to display their production and sales capabilities.

2019 Echemi Animal Health Industry Analysis Forum gets a wonderful completion. As a leading part of chemical business in China and a professional B2B platform, Echemi aims to provide better products and services to global chemical companies, and focuses on products price, market trend, and environment-friendly products. In the future, Echemi will stand ready to work with customers all over the world and Chinese suppliers to strengthen cooperation and create potential value. Echemi will bring new concepts and inject new blood to the industry, and its innovation and energy will trigger fast development and prosperity of the industry.

Company Name: Echemi Group

Contact Person: Betha

Email: info@echemi.com

Phone: +86-0532-80905922 / 89072278

Address: 12F, HuaYin Mansion, No.5, Donghai West Road, Qingdao, China

City: Qingdao

Country: China

Website: https://www.echemi.com

Amazon Release of “Happygram,” Award-Winning Documentary Revealing Mammograms Ineffective for Detecting Breast Cancer in 40% of Women, Those With Dense Breast Tissue


“Happygram is to mammography what Blackfish was to Seaworld.”

Happygram will be released to the public on Amazon on September 27, 2019, in advance of “Breast Cancer Awareness Month” in October.

In March of 2019 the FDA proposed a change to reporting guidelines for the first time in 20 years to include breast density information in mammogram reports that are sent to patients. This information is already collected and provided to the referring physician.

Women advocates had demanded this change for a decade, and were forced to enact state legislation to require “density reporting” while the FDA resisted calls for the change. As a result of this advocacy, 38 states had enacted some type of density notification laws as of 2018, although not all laws required notification to a woman about her own density.

“Dense tissue” refers to having more than 50% non-fatty vs. fatty tissue in the breast. 40% of women who get mammograms have dense breast tissue, which appears white on a mammogram, and can obscure cancers. 70% of invasive cancers occur in women with dense tissue and cancers are often missed by a mammogram for years until they have metastasized.

Density Fact Sheet: http://www.happygramthemovie.com/press.html

Women with dense tissue have a higher risk for breast cancer. Women with > 75% density have 4-6 times the average risk for cancer, a higher risk than if your mother had breast cancer.

“Happygram” is the term for the form letter women receive stating that their mammograms are “normal,” when they actually have an invasive cancer that is missed by the mammogram.

The documentary was inspired by the friendship between Director Julie Marron, of Rhode Island, and Hallie Leighton, of New York, her close friend who died after mammograms missed her breast cancer until it had metastasized. Ms. Leighton was instrumental in the effort to enact the New York state legislation in 2013 before she passed away. The film has won awards across the country, including First Prize for the Providence Film Festival Award at the prestigious Rhode Island International Film Festival.

“Happygram features several women who were not informed of their breast density, of the increased cancer risk that dense tissue poses, or of the fact that mammograms miss cancers when you have dense breasts,” says film director, Marron.

The film explores alternative and adjuvant FDA-approved screening modalities which are more effective at detecting cancer in women with dense tissue. “The film includes interviews with medical experts, politicians, and attorneys advocating for awareness and action on this life-and-death issue,” Marron states. More info: http://www.happygramthemovie.com/about-us-.html

“What stands out in all the stories in this film is that everyone’s cancer was missed for years by the mammogram, and you just don’t hear about that when breast cancer awareness month rolls around,” Marron said. “We hope to highlight the importance of knowing your breast density, so that no woman ever has to go through what these women did.”

Lemon Martini Productions is a woman-owned documentary production company specializing in social justice topics. Other films include the award-winning documentary, Four Games in Fall (http://www.fourgamesinfall.com), which explores topics of science for hire and media manipulation. Man’s Best Fiend, a film currently in production, explores human/wildlife coexistence through a fifteen-year study of the coyote population on Aquidneck Island.

Happygram Intro Movie Clip: https://vimeo.com/335750246

Happygram Gold Standard Movie Clip: https://vimeo.com/335750246

Press: http://www.happygramthemovie.com/press.html

More Information and electronic press kit available at http://www.happygramthemovie.com.

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The New England Center for Children Elects Marco Farsheed to Board of Directors


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Marco Farsheed, new NECC Board of Directors member

“Marco combines business and technical acumen with a desire to improve education for all children,” said Vincent Strully, President and CEO of NECC. “We share a common mission to transform the lives of children with autism worldwide.”

The New England Center for Children® (NECC®), a global leader in education and research for children with autism, announced today the election of Marco Farsheed to the Board of Directors. Mr. Farsheed is an accomplished entrepreneur and private investor.

“The New England Center for Children is fortunate to have Marco Farsheed join our Board of Directors and we will benefit from his entrepreneurial perspective,” said Vincent Strully, President and CEO of The New England Center for Children. “Marco combines business and technical acumen with a desire to improve education for all children. We share a common mission to transform the lives of children with autism worldwide.”

“I am honored and excited to join the NECC Board of Directors. The New England Center for Children has deservedly achieved an international reputation for their education, research and technology to help children with autism,” said Mr. Farsheed. “I have been most impressed with NECC’s ACE® ABA Software System. This curriculum combines NECC’s best-practice, research-based techniques and methodologies, along with reporting tools, to help teachers around the world improve learning for children with autism. I look forward to helping and collaborating with NECC to grow and further their influence in the world of autism services for children.”

Mr. Farsheed is Managing Director of Sina Partners, a family investment and incubation company. He has held executive positions in a number of private and public companies including enEvolv, Cofounder and CEO; Streambase Systems, VP of Strategic Business Development (acquired by TIBCO); Permessa, CEO (acquired by Group Business Software); C-bridge Internet Solutions, EVP of Sales and Marketing (IPO); Platinum Technologies, VP of Business Development and Global Accounts (acquired by CA). Mr. Farsheed has a B.S. in Mechanical Engineering from Northeastern University and an M.B.A. from Harvard Business School.

About The New England Center for Children

The New England Center for Children® (NECC®) is an award-winning autism education center and research institute. Our community of teachers, researchers, and clinicians have transformed the lives of thousands of children with autism worldwide through education, research, and technology. The Center provides comprehensive services to maximize independence: home-based, day, and residential programs, partner classrooms in public school systems, consulting services, the ACE® ABA Software System (http://www.acenecc.org), teacher professional development, and research on educational best practices.

NECC is committed to staff professional development, partnering with local colleges to provide on-site graduate training and degrees at little to no cost to the NECC teacher. The result is a growing pool of exceptional teachers trained in best-in-class methodologies, whether they continue their careers at NECC or move on to public schools or private agencies. The New England Center for Children is based in Southborough, MA, and operates a center in Abu Dhabi, UAE. Learn more at http://www.necc.org.

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“Plump Up Your Profit” Viora Announces the Launch of PlumpRF™, An Innovative Non-Injectable Treatment for Lip Plumping


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Viora’s CORE™ technology enables practitioners to deliver sufficient energy fluence in order to create a rejuvenated effect which increases dermal thickness and restores the lips to their natural red color.

Viora is thrilled to unveil PlumpRF™, the fully customizable, wholly better alternative to injectables. Using advanced technology completely unique to Viora, this revolutionary treatment opens lip plumping up to an entirely new clientele while keeping current patients more satisfied than ever.

The reality is, everyone may want fuller lips, but not everyone wants to be pricked with needles to achieve them, especially if the result ends up looking unnatural. Now, an option exists for all patients to attain natural, full, desirable lips without the risk of discomfort, bruising, and downtime.

This is how it works. PlumpRF integrates Viora’s CORE™ (Channeling Optimized Radiofrequency Energy) Technology, the only delivery system on the market that penetrates precisely into the gentle lip tissue to produce the volumetric heating required to stimulate fibroblast activity, collagen regeneration, and increased blood microcirculation. The result is a look that appears as though it had been surgical, but amazingly was not.

Delivered through the Viora bipolar RF, V-ST hand-piece, 10-minute PlumpRF treatment is quick, safe, painless, and requires no downtime. Plus, the V-ST hand-piece can be utilized to offer many additional facial and body tightening treatments beyond lip plumping, compounding its value. Best long term results are achieved with packages of 6-8 treatments and spread across three months followed by bi-annual maintenance, creating an excellent opportunity for recurring revenue. This, in addition to the financial benefits already realized by simply bypassing the over commoditized market of injectables, make PlumpRF irresistible to patient and practice alike.

Dr. Inna Belenky (Ph.D) | VP Marketing & Clinical Affairs

“Regardless of a person’s genetic makeup of the lips, external factors such as a poor diet, smoking, dehydration, sun damage and more, influence the color, shape and vitality of our lips. Our lifestyle and aging processes lead to the loss of connective tissue (collagen and elastin), moisture and reduced blood microcirculation which can lead to dull color and a thin dermal layer. Viora’s CORE™ technology is a perfect fit for the human lips. CORE™ technology’s ability to cool the epidermal layer makes the treatment totally pain-free, even on such a sensitive area as the lips. In addition, employing CORE™ technology enables practitioners to deliver sufficient energy fluence in order to create a rejuvenated effect which increases dermal thickness and restores the lips to their natural red color. While hyaluronic acid fillers just stuff the lips to produce more volume, the natural regenerative processes achieved by bipolar RF, restore vivid and youthful appearance of the lips.”

Before Viora’s PlumpRF, surgical-level results of lip plumping were only available to clientele who were willing to undergo discomfort and risk. Now, everyone can have the full, beautiful lips they’ve always desired without the pain and encumbrance.

Schedule a financial analysis and technology overview of the PlumpRF treatment with your Viora representative today.

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Genstar Capital Completes Acquisition of OEConnection Holdings LLC


“We are thrilled to join forces with Genstar as we continue to work to expand the OEC footprint and our product and service offerings for customers across the globe,” said Chuck Rotuno, OEC Chairman & CEO.

OEConnection LLC (“OEC” or the “Company”), the leading global automotive technology provider for OEM distribution networks, and Genstar Capital (“Genstar”), today announced they have finalized a deal for Genstar to acquire a majority stake in OEC. This transaction was first announced on August 1, 2019. Current investors, Ford Motor Company and General Motors, will each retain their minority investments in the Company.

Financial terms of the transaction were not disclosed.

OEC was founded in 2000 as a partnership between several original equipment manufacturers (“OEMs”), including Ford and General Motors, to provide high-quality technology solutions to facilitate the sale of original equipment replacement parts between automakers and franchised dealers and their wholesale customers. Since its founding, the Company has expanded to also provide software and technology solutions in the data, supply chain and service segments of OEMs’ businesses. Today, OEC is a leading provider of software solutions and data to the original equipment parts industry and is one of the industry’s only end-to-end comprehensive platforms, serving more than 30,000 auto dealers globally, 36 global OEM brands and more than 135,000 global auto repairers.

“We are thrilled to join forces with Genstar as we continue to work to expand the OEC footprint and our product and service offerings for customers across the globe,” said Chuck Rotuno, OEC Chairman & CEO. “Genstar has an impressive track record of partnering with companies in the software sector to accelerate growth and transformational change.”

About OEC

OEC is the leading global automotive technology provider for OEM distribution networks. Its suite of ecommerce, pricing, supply chain, service, business intelligence, parts cataloging, data solutions, and services helps automakers and their dealer networks sell more OE parts in the collision, fleet, mechanical and retail segments, as well as dealers’ own service lanes. OEC serves more than 30,000 auto dealers globally, 36 global OEM brands and more than 135,000 global auto repairers. The company is headquartered in the greater Cleveland area at 4205 Highlander Parkway, Richfield, Ohio, USA, 44286. Additional information is available at http://www.oeconnection.com

About Genstar Capital

Genstar Capital (http://www.gencap.com) is a leading private equity firm that has been actively investing in high quality companies for over 30 years. Based in San Francisco, Genstar works in partnership with its management teams and its network of strategic advisors to transform its portfolio companies into industry-leading businesses. Genstar currently has approximately $17 billion of assets under management and targets investments focused on targeted segments of the financial services, healthcare, industrial technology and software industries.

Media Contacts

OEC:

Geo Money 330-523-1853

Geo.Money@OEConnection.com

Genstar:

Chris Tofalli

Chris Tofalli Public Relations, LLC 914-834-4334

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UNAIDS and ThoughtFocus Announce IoT Partnership


The Joint United Nations Programme on HIV/AIDS (UNAIDS), through the Health Innovation Exchange, today announced its partnership with ThoughtFocus, a leading technology services company, to establish an Internet of Things (IoT) Center of Excellence. IoT has opened a world of possibilities in health. When connected to the internet, ordinary medical devices can collect invaluable additional data, give extra insight into symptoms and trends, enable remote care, and generally give patients more control over their lives and quality of treatment.

The center will work with health care agencies, manufacturers, Governments, NGOs, communities and other relevant stakeholders to promote the use of IoT in public health and contribute towards establishing shared practices and standards.

The Health Innovation Exchange aims to bridge the disconnect that exists between innovators and implementers in health to fast-track progress to reach Universal Health Coverage (UHC) and other health related Sustainable Development Goals (SDG).

ThoughtFocus, a recognized IoT innovator will make its platform code base available without charge to the Center of Excellence to develop new innovative health solutions. The ThoughtFocus IoT platform is optimized to serve as an affordable, reliable and efficient platform to build and extend IoT solutions. The IoT platform has achieved success in solutions for transportation and logistics, manufacturing and utilities.

Rajiv Goyal, Executive Vice President at ThoughtFocus, said, “ThoughtFocus is committed to making a positive impact on the world and communities we serve. Our partnership with UNAIDS will help others in the Health Innovation Exchange accelerate innovations that address critical health issues of the world.” He highlighted that, “ThoughtFocus worked with the Bill and Melinda Gates foundation and Kohler to build eco-friendly sustainable toilets. We also provided IoT solutions for dairy farmers in rural India. We have demonstrated how IoT improves the lives of tens of thousands of economically challenged individuals and opens up new opportunities for them.”

“Realtime data is critical for transforming healthcare and we are really looking forward to exploiting the potential of IoT and connected devices to improve access and secure supply chain solutions,” said Pradeep Kakkattil, Director, Office of Innovation at UNAIDS, who also expressed his organization’s delight that ThoughtFocus will be joining the Health Innovation Exchange.

About UNAIDS

UNAIDS is a model for United Nations reform and is the only co-sponsored Joint Program in the United Nations system. The co-sponsors include UNHCR, UNICEF, WFP, UNDP, UNFPA, UNODOC, UN Women, ILO, UNESCO, WHO and The World Bank. Since its beginning in 1996, UNAIDS has led and inspired global, regional and local leadership, innovation and partnership. UNAIDS advocacy and leadership has resulted in putting 22 million people living with HIV on life saving treatment in the last 15 years. UNAIDS provides the strategic direction, advocacy, coordination and technical support needed to catalyze and connect leadership from governments, private sector and communities to deliver lifesaving services.

About ThoughtFocus

ThoughtFocus is a privately held technology and services company serving large to middle-market clients in Financial Services, Manufacturing, Aerospace, Higher Education. Clients look to ThoughtFocus for innovative solutions in product engineering, knowledge process outsourcing and digital transformation. The company has over 1,900 employees globally and is one of the fastest growing technology services companies. ThoughtFocus is a technology partner and portfolio investment company of Blackstone, a leading private equity firm.

ThoughtFocus has its US offices in New York City, Milwaukee, Atlanta, Dallas and Irvine with delivery centers in India at Bengaluru, Mysuru, Gurgaon, Hyderabad and in the Philippines at Baguio City.

Image: (Left to Right)

Pradeep Kakkattil, Director, Office of Innovation at UNAIDS

Rajiv Goyal – Executive Vice President, ThoughtFocus

Gunilla Carlsson – Executive Director, UNAIDS

Suman Radhakrishna – Chief Executive Officer (CEO) ThoughtFocus

Shylesh Krishnan – Executive Vice President, ThoughtFocus

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BioFactura Awarded $67.4 Million Advanced Development Contract for its Smallpox Biodefense Therapeutic


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“We look forward to working with BARDA in this new chapter of product development as we bring an important defense to our citizens,” shares Dr. Darryl Sampey, President and CEO of BioFactura

BioFactura, Inc. today announced a contract awarded by the Biomedical Advanced Research and Development Authority (BARDA) valued at up to $67.4 million for the advanced development of its Smallpox Biodefense Therapeutic as a potential medical countermeasure (MCM) for the treatment of smallpox. This product has the potential to fulfill an unmet need in preparedness for a second anti-viral therapeutic with a different mechanism of action to the current stockpile to guard against potential host resistance.

This contract for the development of the Smallpox Biodefense Therapeutic consists of a base phase, valued at approximately $9.5 million, and three option phases over a total of 5 years. Under the base period-of-performance, work will focus on the development of manufacturing processes for the drug components, final product formulation, analytical method development, stability studies and regulatory activities to support formal engagement with the FDA. In addition to the base, the contract also includes U.S. Government options that may be activated to support process optimization and clinical manufacturing, additional non-clinical development studies to support an Investigational New Drug filing, and a first-in-humans Phase 1 clinical study.

While smallpox was declared eradicated in 1980 by the World Health Organization after an extensive vaccination campaign, the threat of bioterrorism and/or inadvertent release remains. Although TPOXX® (Tecovirimat, SIGA Technologies, Inc.) received FDA approval for smallpox treatment in 2018, Variola Virus (VARV), the causative agent for smallpox infections in humans, can become resistant to treatment suggesting that the best medical countermeasure approach would utilize complementary therapeutics. To fill the need for additional treatment options, BioFactura, in partnership with BARDA, is advancing the development of its monoclonal antibody-based Smallpox Biodefense Therapeutic in a stepwise approach building upon years of early product research and development and a strong foundation of cell line, process, analytical and

manufacturing development experience and expertise.

Dr. Darryl Sampey, President and CEO of BioFactura, stated, “This advanced research and development contract award marks the culmination of decades of discovery and development work performed by our team, our partners at the National Institutes of Health and our principal government collaborator Dr. Jay Hooper at the U.S. Army Research Institute of Infectious Diseases. We look forward to working with BARDA in this new chapter of product development as we bring an important defense to our citizens.”

“This government contract for the development of a novel smallpox therapeutic countermeasure is the result of years of cutting edge biotechnology research, the perseverance of forward-thinking scientific entrepreneurs, the risk appetite of loyal investors, and the dedication of the Department of HHS/BARDA to maintain the safety and security of the United States population,” stated Dr. Jeffrey Hausfeld, BioFactura’s Chief Medical Officer and Chairman. “It is truly an evolving American success story and one which as a physician and Chairman of the Board of BioFactura, I am proud to be a part of.”

This project has been funded in whole or in part with Federal funds from the Department of Health and Human Services; Office of the Assistant Secretary for Preparedness and Response; Biomedical Advanced Research and Development Authority, under Contract No. 75A50119C00054.

About BioFactura, Inc.

BioFactura, Inc. (Frederick MD) develops and commercializes high-value biodefense medical countermeasures and biosimilars (i.e., follow-on biologics or generic biopharmaceuticals) using its patented StableFast™ Biomanufacturing Platform, the optimal system for bringing these drugs to market with faster, lower cost, superior-quality manufacture. For over 15 years, BioFactura has been advancing life-saving medicines from the research bench to the patient using its innovative drug development and manufacturing technologies.

Current and past programs include biodefense drugs against smallpox and Ebola, novel medicines for cancer, and low-cost/high-quality biosimilars for autoimmune and infectious diseases. http://www.biofactura.com

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Kiran Mazumdar-Shaw Promises to Enable Universal Access to rh-Insulin by Reducing Prices to Less than 10 US cents /Day for LMICs


At Biocon, we are guided by the conviction that a lifesaving product like insulin cannot be priced out of the reach of those that need it on an everyday basis, whether in advanced economies like the United States or in Africa, or anywhere else on the planet.

Ms Kiran Mazumdar-Shaw, Philanthropist and Founder of Biocon, today, announced her personal commitment towards enabling universal access to high quality insulin by offering recombinant human Insulin (rh-Insulin) at less than 10 US cents / day in low and middle-income countries (LMICs). These countries, which form most of the world, contribute to 80% of the global disease burden.

The announcement was made at an United Nations General Assembly (UNGA) side meeting on innovation and universal health access convened by UNAIDS Health Innovation Exchange, in the presence of the President of Ethiopia, the First Lady of Namibia, Health Ministers from Botswana and Malawi, and representatives from the Private Sector and Development Agencies. The forum on ‘Accelerating Innovations and Investments for Access to Healthcare’ was co-sponsored by UNAIDS and the Center for Global Health and Development.

Biocon Biologics’ recombinant human insulin has been developed using the scientific expertise and world class R&D and manufacturing facilities that have allowed it to bring multiple biosimilar medicines to the US and Europe. The Company is committed to use its science, scale and expertise to shift the access paradigm for patients in need of insulins. Biocon is a leading global insulins player with over 15 years of experience in addressing the needs of patients with diabetes, having provided over 2 billion doses of human insulin worldwide, thus far.

The announcement by Ms Kiran Mazumdar-Shaw is guided by her conviction that a life-enabling product like insulin cannot be priced out of the reach of those that need it on an everyday basis, whether in the United States or in Africa.

Biocon’s Recombinant Human insulin offer of less than 10 US cents / day in LMICs is for vials sourced by the government directly from Biocon, assuming an insulin dosage of 40 IU per day.

Currently, the blended median patient prices in LMICs are US$ 9** per 10 ml vial translating to 36 US cents/ day. The current US list price in retail is over US$ 5*** / day.

Biocon, an India-based global biopharmaceuticals company is committed to affordability and access and will work with healthcare systems and payers worldwide to ensure that Insulin pricing is not a constraint to the well-being of individuals and of communities.

She also called upon insulin delivery devices manufacturers to join the movement towards ensuring affordable access to insulins by ensuring lower prices for the insulin pens and needles required to administer the drug.

Biocon Biologics is willing to work with governments to ensure ways to overcome price barriers, including through special pricing and setting up low-cost manufacturing facilities via public-private partnerships in order to address the huge cost burden borne by people with diabetes.

In high income regions like the US, Biocon believes it can make a dramatic impact on the current insulin pricing crisis if its ongoing discussions with the regulators allow the Company to scientifically bridge its clinical data to US reference product.

This will reduce clinical development costs and bring the product years earlier to patients who cannot afford insulin therapy.

Ms Kiran Mazumdar-Shaw is a healthcare visionary and philanthropist. Her vision is to enable universal access to high quality medical products, particularly to address the global chronic disease burden. She is a pioneer of India’s biotech industry and founder of the country’s leading biotechnology enterprise, Biocon. A thought leader and a global influencer, she has been ranked among ‘World’s 25 Most Influential People in Biopharma’ by Fierce Biotech. She was No. 1 in the Business Captains category on the ‘Medicine Maker Power List’ 2018, an index of the 100 most influential people across the globe in the field of medicine, where she has been among the Top 10 continuously since 2015.

She is a full-term member of the MIT Corporation, the board of trustees of the Massachusetts Institute of Technology (MIT), and member of the National Academy of Engineering, US. She is on the board of directors of the US-India Business Council (USIBC) and has previously served as a member of the board of trustees of the US Pharmacopeial Convention (USP). She has been conferred with the Advancing Women in Science and Medicine Award for Excellence by the Feinstein Institute for Medical Research, US and Othmer Gold Medal by the Chemical Heritage Foundation, US.

Biocon Limited, publicly listed in 2004, in India is a fully-integrated, innovation-led global biopharmaceuticals company committed to enhance affordable access to complex therapies for chronic conditions like diabetes, cancer and autoimmune diseases, benefitting a billion lives.

Biocon Biologics is its wholly owned subsidiary engaged in providing affordable access to high quality biosimilars to patients across the globe. It is driven by its vision to transform patients’ lives across the globe through innovative and inclusive healthcare solutions. Biocon’s rh-Insulin and Insulin Glargine products are already benefiting people with diabetes in many emerging and developed markets. In multiple countries like Mexico and Malaysia, nearly all insulin-requiring diabetics take Biocon’s insulins. Its rh-Insulin is registered in over 40 countries worldwide.

The Company is serving patients in U.S., EU, Japan, Latin America, Africa, Middle East and Turkey and the Asia-Pacific regions through its high quality biosimilars for diabetes and cancer. Biocon’s large scale, state-of-the-art bio-manufacturing facilities are qualified by various regulatory agencies from developed and emerging markets.

Note:

** Source: BMJ Global Health 2019: Insulin Prices Availability and affordability in 13 low income and middle income countries

*** Source:goodrx.com

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Media Enquiries:

Seema Ahuja: seema.ahuja@biocon.com / +91 997 231 7792

Dr Bobby John: bj@aequitas.co / +1 202 902 9401

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Apex Catalyst Group, A Business Management Firm That Transforms Entrepreneurs Into Leaders Announces Rebranding and Launch Party


To celebrate this momentous occasion, Apex Catalyst Group is hosting a party at WeWork in Fort Worth, TX on October 1st, 2019 from 5:00-7:00PM CST. The party will also be streamed live over Facebook for those that want to join the party, right from their office.

“It is important for business owners to take time to celebrate their growth, accomplishments and milestones. I find myself reminding my clients of that frequently and it is only appropriate that I take this moment to celebrate the company’s achievements”, says Sandi Mitchell, CEO of Apex Catalyst Group. Sandi is a certified executive coach and EOS® Entrepreneurial Operating System Professional Implementer who specializes in creating inspired work environments, aligning teams to maximize potential, and building work ecosystems built on trust and clear communication.

Apex Catalyst Group has worked with small to medium-sized businesses and corporations globally, concentrating in the Dallas-Fort Worth area, for the past six years with a focus on establishing bold organizations unafraid to change. Prior to rebranding, APEX Leadership Mastery was managed solely by Sandi Mitchell, and has grown to include a team of business experts who specialize in HR, sales, operations, marketing and more. Supported by a hand-picked team of elite advisors, the new Apex Catalyst Group will guide entrepreneurs on a strategic roadmap towards intentional success.

In addition to the launch party happening on October 1st, 2019, the rebranding of Apex Catalyst Group includes a completely redesigned website, a social media marketing campaign on Facebook and LinkedIn, a revamped logo, graphics, and print materials.

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Five Consumer Safety Guidelines When Vaping from Integrated Healthcare Solutions


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Legitimate CBD vaporizers are different from e-cigarettes and do not draw carcinogens into the body. Consumers should always check for a Certificate of Analysis (COA) on packaging.

While vaping options are vast, not all cartridges are alike. That’s why we’ve put together five general safety guidelines to help consumers find quality vaporizers and make sure they get the outcome they expect.

As a result of hundreds of lung disease cases linked to e-cigarettes and vaping, Integrated Healthcare Solutions Inc. (IHS), a leading innovator in cannabidiol (CBD) products, has released new guidelines to help consumers choose safe, legal and effective CBD vaporizers.

According to Dorian Knape, CEO of woman-owned IHS, many of the cases stem from products that contain THC, nicotine and vitamin E acetate as well as impurities, so consumers should do their research before vaping.

“While vaping options are vast, not all cartridges are alike,” said Knape. “Consumers can take a few simple steps to make an informed buying decision. That’s why we’ve put together five general safety guidelines to help consumers find quality vaporizers and make sure they get the outcome they expect.”

1) Choose a Vaporizer Instead of an E-cigarette – Vaporizing is different from an e-cigarette and does not draw carcinogens into the body. Many e-cigarettes contain propylene glycol (PEG) and nicotine-flavored juices, which can be harmful, whereas Urban Bio vaporizers blend naturally derived floral terpene profiles with CBD.

2) Check the Certificate of Analysis (COA) – Consumers should be wary of products that lack a COA, which involves testing by an independent lab for THC, heavy metals, microbials, pesticides and other concentrates. Most reputable CBD manufacturers will feature a QR code on their product labels, which enables consumers to access the COA by lot number. The COA should note THC levels or ensure that contents are THC-free. Consumers should also make sure the COA indicates the product does not contain vitamin E acetate, solvents, microbes, pesticides and heavy metals. These additives can affect the body’s cells, causing inflammation of the lungs.

3) Investigate Cartridge Content and Brand Legitimacy – Avoid low-grade ingredients such as polypropylenes (PG) and PEG, vegetable glycerin (VG), nicotine and psychosomatic substances such as THC. Choose an established company and brand with address, web site and phone number clearly on product packaging.

4) Know Your Source – Don’t buy from street vendors or sources that can’t produce product documentation such as lot or batch numbers and current COAs, which indicate a track and trace process. Before choosing a vendor, consult your healthcare provider to determine safety.

5) Investigate the Power of Terpenes – Terpenes are natural aromatic compounds that produce a spectrum of scent associated with foods, perfumes, etc. Different strains of terpenes carry different therapeutic benefits. Established companies will clearly state the terpene profiles within their vape cartridges. This broadens the choice of effect sought by consumers and eliminates the need for nicotine and THC.

“At IHS, we’ve taken extensive steps to provide consumers with exceptionally pure vaporizers that are free of THC, nicotine, vitamin E acetate, heavy metals, microbes and other contaminants – and we back that up with third-party lab testing as demonstrated by our COAs,” said Knape. “Consumers can be confident when they vaporize with our Urban Bio Pure Inhalation Cannabidiol (PIC) Cartridges.”

Sourced from hemp extract, Urban Bio PIC Cartridges are high in antioxidants and available in nine organic terpene profiles. Each 400 MG, one-gram cartridge features a 510-threaded connection for universal compatibility. In addition to PIC Cartridges, the Urban Bio product line includes transdermal relief creams, rejuvenation skin creams, gummies, and water-soluble Oral Drops as well as Pure Nano Drops.

Integrated Healthcare Solutions Inc. is a woman-owned enterprise and leverages the collective talents of more than 130 employees to help people stay active and live pain free. The company has a 30-year track record in healthcare through its affiliates, including medical devices by VQ OrthoCare, exercise and rehabilitation by VQ ActionCare and certified-organic nutrition by Pucker Urban Farms. Today, IHS boasts the power of its proprietary nano-amplified CBD as a path to maintaining wellness, supported by a rigid quality assurance program and an insistence on product purity. The company markets its growing portfolio of CBD products and services directly to consumers, through premier retail and wholesale channels, and through established medical professionals.

For more information, visit http://www.ihsinc.com or call 949-794-3400.

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