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How to Better Understand Potential Toxicity, Upcoming Webinar Hosted by Xtalks

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Register for this webinar to learn about various drug screening assays that are available for identifying potential DDI in vitro.


TORONTO (PRWEB)

Drug-drug interactions (DDI) resulting in adverse outcomes cause approximately 3% of all hospitalizations annually in the United States. This costs the health care system over a billion dollars. Fortunately, many aspects of DDI are predictable based on the increasing understanding of the mechanisms of altered absorption, distribution, metabolism and excretion (ADME).

Register for this webinar to learn about various drug screening assays that are available for identifying potential DDI in vitro. Drug screening assays improve drug safety and allow for the prioritization of drug candidates. The pregnane X receptor (PXR) and several other important xenobiotic sensing and drug metabolism inducing systems will be described. These include Aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), Farnesoid X Receptor (FXR) and Nuclear factor-erythroid factor 2-related factor 2 (Nrf2).

The featured speaker will also discuss how in vitro assays can be used for species extrapolation of pharmacokinetic interactions for common laboratory animal models. These in vitro assays save time and money lost from pursuing candidates that may fail in animal or clinical trials.

Join Jack Vanden Heuvel, Professor of Molecular Toxicology, Pharmacology & Toxicology Undergraduate Program Coordinator, Penn State University; CSO, INDIGO Biosciences, for the live webinar on Friday, April 29, 2022, at 1pm EDT (10am PDT).

For more information, or to register for this event, visit Nuclear Receptors and Drug-Drug Interactions: How to Better Understand Potential Toxicity.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com

For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

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