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ASL is delighted to announce asthma & allergy friendly® CERTIFIED building materials are now approved by USGBC’s LEED® Building Rating System

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ASL is delighted to announce asthma & allergy friendly® CERTIFIED building materials are now approved by USGBC’s LEED® Building Rating System

ASL is delighted to announce asthma & allergy friendly® CERTIFIED building materials are now approved by USGBC’s LEED® Building Rating System

“This recognition by USGBC reinforces our commitment to promoting healthy indoor environments through certification, education, and science,” said Dr. John McKeon, CEO of Allergy Standards


Dublin, Ireland (PRWEB)

Allergy Standards Ltd. (ASL) announced today that its asthma & allergy friendly® certification standards for building materials have been approved by the U.S. Green Building Council (USGBC) LEED® Building Rating System, making it a qualified third-party certification for the LEED v4.1 low-emitting materials credit. LEED is a widely used green building rating system run by USGBC, and provides a framework for healthy, efficient, carbon and cost-saving green buildings.

Resilient and textile flooring, paint, and insulation products that are CERTIFIED asthma & allergy friendly® are now compliant with LEED Low-Emitting Materials credit requirements.

The asthma & allergy friendly® Certification Program takes a whole-of-home approach to healthier indoor air, and its suite of over 50 certification standards assess products as diverse as electrical appliances, bedding, cleaning products, and building materials. The standards address a wide range of triggers of asthma and allergy in the indoor environment. For building materials, Volatile Organic Compounds (VOCs) are an important factor in ensuring a healthier indoor environment.

The asthma & allergy friendly® Certification Program sets strict criteria in terms of VOC emissions for paint, insulation, and flooring, and in terms of VOC content for paint. It is these criteria that have been approved by USGBC for LEED low-emitting materials credits.

“Transforming our buildings and spaces requires partnerships with organizations that are committed to creating products that support the LEED rating system,” said Peter Templeton, president and CEO, USGBC. “Allergy Standards Ltd. understands the value of LEED and using products that promote the health and wellness of building occupants.”

ASL’s certification standards also go beyond VOCs to look at the broader impact of these product types on the indoor environment. Testing also assesses allergen removal from flooring, particulate and dust release during insulation installation, and performance testing for paint. In addition, a detailed review of the constituent materials of each product is undertaken, to ensure that potentially hazardous chemicals are either not present, or present at suitably low levels.

ASL’s certification clients all over the world can now have their products included in LEED-certified building and renovation products. Dr. John McKeon, CEO of Allergy Standards, said, “There is great alignment between ASL’s mission to make the right to breathe clean air a reality, and the LEED approach to healthy and green buildings. It is imperative that manufacturer claims around healthier indoor environments are supported by good science. This recognition by USGBC reinforces our commitment to promoting healthy indoor environments through certification, education, and science.”

About ASL

Our mantra is design thinking and innovation for the air aware consumer. As an independent, international certification company, we create peer-reviewed, scientific standards for a wide range of products and services to determine their impact on indoor air quality. ASL’s intellectual property portfolio includes unique protocols for products to be CERTIFIED asthma & allergy friendly®. Our mission is to make the United Nations human right to breathe clean air a reality, through science (Standards), education (Academy) and innovation (Institute). http://www.allergystandards.com/

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Health: Mental Health

Viewing the world through jerk-colored glasses

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Assuming there are potential enemies everywhere can compel us to become a villain ourselves.

Mistrusting everyone and assuming the worst of others might offer some protection, but cynicism is a doubled-edged sword.

As long as you think the world is filled with evil and take up your proverbial sword, all you’ll really be doing is feeding your own inner demon.


MONTREAL (PRWEB)

Author Lemony Snicket aptly described the fallacy of using cruelty to deal with cruelty when he said, “if everyone fought fire with fire, the whole world would go up in smoke.” When researchers at PsychTests.com looked into the personal and social consequences of assuming the worst of people, they discovered that cynics who think the world is a cruel place may use it as a reason to mistreat others.

Analyzing data collected from 12,259 people who took the Emotional Intelligence Test, PsychTests’ researchers compared the attitudes, beliefs, and personality of people who assume the worst of others (“Cynics”) and those who don’t (“Non-Cynics”). Here’s what the results revealed:

AS EXPECTED, CYNICS TEND TO BE RATHER CLOSED-MINDED.

  • 52% of Cynics believe they are better off distrusting everyone (vs. 5% of Non-Cynics).

  • 41% assume that most non-profit organizations use their donations dishonestly (vs. 6% of Non-Cynics).

  • 35% refuse to accept opinions that differ from their own (vs. 3% of Non-Cynics).

  • Paradoxically, 44% of Cynics tend to blindly adopt their family’s or friends’ beliefs (vs. 19% of Non-Cynics).

PREDICTABLY, CYNICS ARE NOT ALWAYS ALTRUISTIC AND CAN BE EGO-CENTRIC.

  • 15% of Cynics have never donated to charity (vs. 5% of Non-Cynics).

  • 18% have never given food or money to a homeless person (vs. 11% of Non-Cynics).

  • 15% said that they would rather have powerful, inauthentic friends than real, uninfluential friends (vs. 2% of Non-Cynics).

  • 22% would rather be feared than loved (vs. 3% of Non-Cynics).

  • 43% have dated or befriended someone strictly to gain something (vs. 23% of Non-Cynics).

CYNICS MAY SOMETIMES OFFER UNSOLICITED AND POTENTIALLY HARSH ADVICE.

  • 14% of Cynics think it’s okay to tell an obese stranger how to lose weight (vs. 3% of Non-Cynics).

  • 18% would have no problem telling a homeless person to get a job (vs. 5% of Non-Cynics).

  • 29% believe it’s a good idea to encourage a depressed person to “toughen up” (vs. 10% of Non-Cynics).

  • 16% consider it acceptable to tell a mother that her son will turn out gay if she continues to allow him to play with dolls (vs. 2% of Non-Cynics).

CYNICS ARE MORE LIKELY TO STRUGGLE WITH A NUMBER OF PERSONAL AND PSYCHOLOGICAL ISSUES.

  • 63% of Cynics find it hard to express their feelings (vs. 18% of Non-Cynics).

  • 59% are unwilling and/or unable to accept compliments (vs. 25% of Non-Cynics).

  • 51% admitted that they change their attitude, behavior, or appearance in order to please others (vs. 12% of Non-Cynics).

  • Deep down, 55% of Cynics desperately want to be liked by others and have a strong need for approval (vs. 40% of Non-Cynics).

  • 26% are unhappy with their lives (vs. 5% of Non-Cynics).

“When you come into contact with someone who is staunchly cynical, there’s a good chance that it stems from an unresolved issue or hang-up,” explains Dr. Ilona Jerabek, president of PsychTests. “For example, in our study, 63% of the Cynics said that they frequently put other people’s needs ahead of their own even when they don’t want to, and 62% feel they have been taken advantage of one too many times. This is telling: more than half have been seriously mistreated, and when emotional injuries remain unhealed and unresolved, we carry them with us. This is what leads Cynics to see the world as cruel and to feel that the only logical response is to be cruel themselves…or to strike first by biting the snake before it can bite them, even if the snake is only imagined. Unfortunately, this approach to life offers little in terms of creating a sense of security or happiness. Granted, there are circumstances when you’ve got to be tough and assertive to deal with an unscrupulous person, but fighting cruelty with cruelty is not a path to resolution. And the reality is, as long as you think the world is filled with evil and take up your proverbial sword, all you’ll really be doing is feeding your own inner demon.”

What’s your EQ? Find out the Emotional Intelligence Test: at https://testyourself.psychtests.com/testid/3979

Professional users, such as HR managers, coaches, and therapists, can request a free demo for this or other assessments from ARCH Profile’s extensive battery: http://hrtests.archprofile.com/testdrive_gen_1

To learn more about psychological testing, download this free eBook: http://hrtests.archprofile.com/personality-tests-in-hr

About PsychTests AIM Inc.

PsychTests AIM Inc. originally appeared on the internet scene in 1996. Since its inception, it has become a pre-eminent provider of psychological assessment products and services to human resource personnel, therapists and coaches, academics, researchers and a host of other professionals around the world. PsychTests AIM Inc. staff is comprised of a dedicated team of psychologists, test developers, researchers, statisticians, writers, and artificial intelligence experts (see ARCHProfile.com).

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Mobile Community Health Leadership Awards Honors AltaPointe Health Recreational Therapist Megan James

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Megan James (center), recreational therapy coordinator for AltaPointe Health’s two psychiatric hospitals, was recognized at the Mobile Community Health Leadership Awards.


MOBILE, Ala. (PRWEB)

If you follow the sounds of joy and laughter echoing through BayPointe or EastPointe Hospital, you’re likely to find Megan James, CTRS, in the midst of it all. Megan serves as the recreational therapy coordinator for AltaPointe Health’s two psychiatric hospitals.

Every day, Megan leads a diverse range of activities including games, exercises, sports, and art, with the aim of enhancing the well-being of each patient and progressing towards their treatment goals. However, this Saturday, the spotlight was on Megan herself and her remarkable achievements.

Megan was honored at the Mobile Community Health Leadership Awards, hosted by the Mobile Medical Museum. These awards honor local leaders who demonstrate exceptional dedication in education, awareness, and action regarding Mobile’s most pressing community health concerns.

Dr. Daryn Glassbrook, Executive Director of the Mobile Medical Museum, explained, “We have not previously recognized a recreational therapist and saw this as a prime opportunity to shed light on this aspect of community health and acknowledge Megan’s outstanding work.”

During the ceremony, Megan was commended as “a passionate advocate for recreational therapy, utilizing therapeutic activities and community reintegration to assist individuals with disabilities or debilitating conditions in regaining skills, improving mood, and fostering social connections.”

In order to enhance her recreational therapy efforts, Megan has also trained her two goldendoodles as Certified Therapy Dogs, affectionately named Zeke and Ollie. These furry companions accompany Megan to the hospitals, providing emotional support to both patients and fellow staff members.

Nicolette Harvey, associate director for AltaPointe’s hospitals, expressed immense pride in Megan’s accomplishments, stating, “We are incredibly proud of Megan and consider ourselves fortunate to have her as an integral part of the treatment teams at BayPointe and EastPointe. Our patients face significant challenges, but Megan consistently goes above and beyond to enhance their experience and cultivate an atmosphere of encouragement and enthusiasm.”

Megan was further commended for her commitment to passing on her expertise to the next generation of recreational therapists, serving as an adjunct instructor at the University of South Alabama.

Megan James’ unwavering dedication to improving the lives of psychiatric patients through recreational therapy has earned her well-deserved recognition. Her exceptional contributions and compassionate approach continue to make a lasting impact within the community.

ABOUT ALTAPOINTE

AltaPointe Health is an extensive mental health and family medical healthcare system. Our clinicians provide more than 1.3 million hospital, outpatient, residential and crisis services annually. Rounding out the continuum, AltaPointe operates two psychiatric hospitals serving children and adults, 20 outpatient behavioral healthcare clinics, and a behavioral health crisis center. AltaPointe’s providers also serve as the administration and faculty for the University of South Alabama, College of Medicine-Department of Psychiatry.

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Genomenon Wins Best of Show Award at Bio-IT World 2023 Conference and Expo

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Genomenon wins Bio-IT Best of Show 2023

This recognition aptly demonstrates how we enable pharmaceutical companies that are pioneering development of therapies for orphan diseases with Genomic Intelligence.


ANN ARBOR, Mich. (PRWEB)

Genomenon Inc., a genomic intelligence company, today announced that it was awarded Best of Show at Bio-IT World Conference and Expo 2023 for its independent genetic disease assessment, which starts with calculating rare disease prevalence. Each year, the Best of Show Awards program at Bio-IT World recognizes innovative product solutions to important problems facing the Life Sciences industry. Genomenon’s offering was one of 33 new products considered for this prestigious award at last week’s 22nd annual event in Boston, MA.    

Accurately estimating the prevalence of a rare disease is particularly challenging for orphan drug developers. Missing even one published paper that documents pathogenic and likely pathogenic gene variants implicated in rare genetic diseases can dramatically affect the resulting estimate. Underestimating disease prevalence can compromise fund-raising efforts for rare disease drug programs, whereas overestimating can make it difficult to meet clinical trial recruitment goals.

For companies targeting rare diseases, Genomenon’s disease prevalence report provides a more complete understanding of the genetic prevalence of autosomal recessive (AR) diseases. Part of Genomenon’s new Genomic Intelligence portfolio, this offering leverages both the Mastermind® Genomic Language Processing (GLP) AI technology and exhaustive knowledgebase of human genomic evidence with genomic intelligence.

Genomenon delivers an insight-rich curated dataset and comprehensive prevalence report that includes an updated calculation of estimated genetic prevalence that orphan drug companies can use to validate market potential for new therapies under development. In a recent application, Inozyme Pharma partnered with Genomenon to update the disease prevalence estimation for ENPP1 Deficiency. Genomenon’s revised estimate was more than three times the previous estimate, and results were published in the Orphanet Journal of Rare Diseases (Chunn et al, 2022, https://ojrd.biomedcentral.com/articles/10.1186/s13023-022-02577-2).

“We are honored that our new methodology for estimating and validating Rare Disease Prevalence was chosen by the awards committee as one of the most valuable and innovative solutions for the Bio-IT community,” said Genomenon CEO Mike Klein. “This recognition aptly demonstrates how we enable pharmaceutical companies that are pioneering development of therapies for orphan diseases with Genomic Intelligence.”    

About Genomenon

Genomenon is a genomic intelligence company dedicated to improving the quality of life of genetic disease and cancer patients by making genomic information actionable. Blending the power of AI with the precision of genomic expertise, the company empowers pharmaceutical companies and the clinical diagnostic community with empirical genomic evidence and insights that both support the development of novel therapeutics and speed diagnostic assessments and treatment recommendations.    

For more information, visit Genomenon.com.    

About Bio-IT World Conference and Expo

The Bio-IT World Conference & Expo is the world’s premier event showcasing the technologies and analytic approaches that solve problems, accelerate science, and drive the future of precision medicine. For more than 20 years, the event has united a community of leading life sciences, pharmaceutical, clinical, healthcare, informatics, and technology experts in the fields of biomedical research, drug discovery & development, and healthcare from around the world.

Read more about this annual precision medicine event at https://www.bio-itworldexpo.com/

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The Fusing’s Shop Introduces New Glass Dab Straw for Enhanced Concentrate Dabs

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The Fusing Shops Glass Dab Straw

We have invested significant time and effort into developing a product that enhances the concentrate smoking experience.


HIGHLAND PARK, N.J. (PRWEB)

The Fusing Shop (TFS) is a small, family-owned business based in Highland Park, New Jersey. The shop is a design, manufacturing facility and a glass blowing teaching studio. People come from all over NY, PA, and NJ for glass blowing classes in NJ. TFS offers hands-on experience working with glass, and it’s a unique opportunity to manipulate the hot glass in the fire.

The Fusing Shop has always been committed to delivering top-of-the-line products that cater to the evolving needs of the smoking community. With the increasing popularity of concentrates, the demand for an efficient and reliable smoking tool has grown exponentially. Recognizing this, The Fusing Shop has developed a cutting-edge solution with their new glass dab straw.

One of the key advantages of The Fusing’s Shop glass dab straw is its premium quality. The dab straw is made from high-grade borosilicate glass and is kiln annealed, ensuring maximum durability and heat resistance. In addition, the construction of the dab straw gives users a clean and smooth hit every time, without any unwanted flavors or aftertaste.

The glass dab straw features a sleek and ergonomic design, making it easy to hold and use. Its compact size allows for discreet and on-the-go consumption, enabling enthusiasts to enjoy their concentrates wherever they may be. The simplicity of the dab straw eliminates the need for complicated setups and excessive equipment, providing a hassle-free experience.

Another standout feature of TFS glass dab straw is its versatility. The straw is compatible with a wide range of cannabis concentrates, including shatter, wax, and oil. This flexibility allows users to experiment with different products and explore various flavors, enhancing their overall smoking experience.

To ensure the best smoking experience, The Fusing Shop has conducted rigorous testing and quality control measures on its glass dab straw. The dab straws are made by hand right here in the USA. In addition, the glass straws have undergone extensive evaluations to meet the highest industry standards, guaranteeing their safety and effectiveness. As a result, customers can have complete confidence in the reliability and performance of this innovative smoking accessory.

“We are thrilled to introduce our new glass dab straw to the market,” said Sim W., CEO of The Fusing Shop. “We have invested significant time and effort into developing a product that enhances the concentrate smoking experience. The Fusing Shop glass dab straw delivers on both functionality and style, providing enthusiasts with a superior way to enjoy their favorite concentrates.”

The Fusing’s Shop glass dab straw is now available for purchase through their website, http://www.thefusingshop.com. Customers can choose from a variety of stylish designs and colors, allowing them to personalize their smoking sessions to reflect their unique style.

For more information please visit The Fusing Shop website.

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Evidence Prime Wins Main Prize for the Best Technological Solution in “The Eagle of Innovation” Competition organized by the editors of “Rzeczpospolita” daily in Poland

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Evidence Prime with it’s Laser AI were awarded the most prestigious Central European award for innovative startups – the Eagle of Innovation.


GDARISK, Poland (PRWEB)

The price has been awarded to Evidence Prime for its flagship product, Laser AI. This advanced solution, based on natural language processing (NLP) and artificial intelligence (AI), helps life sciences organizations around the world make data-driven decisions, streamline processes, and enhance operational efficiency. Laser AI has significantly improved the way organizations manage and analyze vast amounts of data, supporting the creation of so-called Living Systematic Reviews (LSR) – systematic reviews updated on an ongoing basis.

“We are thrilled to receive the main prize for Best Technological Solution in the Eagle of Innovation competition,” said Pawel Kunstman, President of Evidence Prime. “In 2018, we committed all our efforts to the development of Natural Language Processing technologies capable of handling the overwhelming volume of evidence that needs to be analyzed to make the right healthcare decisions. This award is a testament to the hard work and dedication of our talented team, which made achieving this goal possible. We are grateful for this honour and remain committed to delivering cutting-edge solutions that drive transformative change in the life sciences industry.”

Evidence Prime received the main prize in the category of the Best Technological Solution during the Eagle of Innovation award ceremony on the 24th of May, 2023, in Gdańsk, Poland. The event gathered influential leaders, industry experts, and key stakeholders to celebrate the achievements of innovative companies and their contributions to the European technological landscape.

About Evidence Prime:

Evidence Prime is a global leader in the market of evidence-based healthcare guidelines and systematic review authoring, focusing on innovative, AI-driven tools for this market. Its flagship product, Laser AI, is a revolutionary system for automating the development of systematic reviews in healthcare. Already in use by leading US and German governmental institutions as well as major corporations, Laser AI streamlines the review process, allowing for more efficient and accurate analysis of healthcare data. With its commitment to data security, Evidence Prime stands out as the most secure Software-as-a-Service (SaaS) provider in its domain, bringing the safest and most effective solutions to accelerate research efforts. For more information about Evidence Prime, its groundbreaking products, and its commitment to security, visit https://laser.ai and https://evidenceprime.com.

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Senior Care Franchise Right at Home Targets Baton Rouge Expansion, Looking to Meet with Qualified Prospective Franchisees Wanting to Make a Difference in Their Community

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BATON ROUGE, La. (PRWEB)

Right at Home, the 700-plus location in-home care concept helping seniors and adults with disabilities live comfortably at home, is looking to expand in Baton Rouge, Louisiana. The opportunity gives local entrepreneurs a chance to make a difference in their communities and provide peace of mind to families needing care.

Right at Home employs professionally trained caregivers to provide care and assistance to seniors and adults with disabilities who wish to remain in the comfort and safety of their own home or current living arrangement. With over 28 years of experience providing essential care in more than 700 locations across seven countries, Right at Home has become one of the world’s largest in-home care franchises.

With persons aged 65 and over making up 14.2% of the population, Baton Rouge is primed for Right at Home’s services. Additionally, the capital city has been growing as a hotspot for new businesses in recent years. In fact, the percent of new companies in Baton Rouge experienced quarter-over-quarter growth 13 of the last 15 quarters, while more than 3,300 new establishments exist in the region compared to Q1 2018.

“Right at Home starts with our passionate franchise owners, and we’re excited to partner with the people of Baton Rouge,” said Jennifer Chaney, Vice President of Franchise Development. “We are seeking passionate individuals who aren’t just looking for a business to make a living. Entrepreneurs should choose Right at Home to make a positive impact on their communities and the people for whom they provide care. Our mission is to improve the quality of life for everyone that we serve.”

Currently, Right at Home doesn’t have a presence in the market, but already has three territories within the state of Louisiana. With its eyes on Baton Rouge, the industry-leading in-home care concept is seeking franchise partners to provide its much-needed services within two territories in the market.

Right at Home is seeing an increased demand for quality in-home care services across the country as the baby boomer generation reaches its senior years. During 2020 and 2021, the franchise not only survived the height of the pandemic but came out of it stronger than ever– exceeding growth goals by 40%. And in 2022, Right at Home picked up even more momentum as it continued to bring its best-in-class in-home care services to families in new markets across the country. This year, Right at Home is looking forward to building on that growth, including in Baton Rouge.

ABOUT RIGHT AT HOME:

Founded in 1995, Right at Home offers in-home care to seniors and adults with disabilities who want to live independently. Most Right at Home offices are independently owned and operated and directly employ and supervise all caregiving staff. Each caregiver is thoroughly screened, trained and bonded/insured before entering a client’s home. Right at Home’s global office is based in Omaha, Nebraska, with more than 700 franchise locations in the U.S. and six other countries. For more information on Right at Home, visit http://www.rightathome.net or read the Right at Home blog at http://www.rightathome.net/blog.

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Elevating the Human Experience in Healthcare through the Lived Experience of Patients & Families

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Over the last two years, more healthcare organizations are engaging the voices of patient and family advisors.


NASHVILLE (PRWEB)

The Beryl Institute releases “Listening Organizations: Elevating the Human Experience in Healthcare through the Lived Experience of Patients & Families,” identifying ways organizations are acting on the feedback of patient and family advisors (PFAs) and improving care experience. The paper includes the global contributions of pioneers, leaders and volunteer advisors in the field of patient and family engagement, acknowledging the current gaps in advisor utilization and recommending ways to elevate their voice in strategic healthcare improvement. The paper highlights success stories of listening organizations and takeaways for becoming one.

Key takeaways include:


  • PFAs are considered important, but their lived experience is not always fully appreciated by healthcare organizations.

  • Listening organizations embed diverse patient and family advisors into committees, education and research, and in strategic planning.

  • Elevating the role of PFAs requires partnerships with leadership, providers and the staff.

“Over the last two years, more healthcare organizations are engaging the voices of patient and family advisors,” said Jason Wolf, President & CEO of The Beryl Institute. “Increased engagement is a good first step toward the evolution of PFA utilization, but it is the power of listening to the lived experience through this engagement and taking action on the feedback that will impact improvement efforts.”

To access the executive brief, PX paper, and patient reflection visit https://www.theberylinstitute.org/page/PXPapers

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About The Beryl Institute

The Beryl Institute is a global community of healthcare professionals and experience champions committed to transforming the human experience in healthcare. As a pioneer and leader of the experience movement and patient experience profession for more than a decade, the Institute offers unparalleled access to unbiased research and proven practices, networking and professional development opportunities and a safe, neutral space to exchange ideas and learn from others.

We define the patient experience as the sum of all interactions, shaped by an organization’s culture, that influence patient perceptions across the continuum of care. We believe human experience is grounded in the experiences of patients and families, members of the heal

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Complimentary In-Home Evaluation by Assisting Hands Home Care for Senior Veterans

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veteran-home-care

Millions of America’s senior citizens are veterans or surviving spouses of veterans. As these heroes age, home is where they want to spend their senior years—surrounded by their favorite people and familiar things. We are here to help!


MANSFIELD, Texas (PRWEB)

Assisting Hands Home Care provides specialized veteran home care services to support elderly veterans who may face unique challenges as they age, including physical and mental health conditions that can make it difficult to perform daily tasks.

The veteran home care services offered by Assisting Hands Home Care are designed to provide compassionate and personalized care to meet the specific needs of each individual veteran.

Assisting Hands Home Care is committed to providing the highest quality senior in-home care to its veteran clients. Caregivers are trained to provide assistance with activities of daily living, such as bathing, dressing, grooming, and meal preparation, as well as companionship services to help alleviate loneliness and provide emotional support. Additionally, they are experienced, compassionate, and dedicated to meeting the unique needs of each individual veteran. The company offers flexible scheduling to ensure that clients receive the care they need when they need it.

Non-medical veteran home health care is provided by Assisting Hands Home Care in Mansfield, TX, and the surrounding areas for veterans and their spouses who are eligible for VA benefits. Assisting Hands licensed caregivers will provide veterans with high-quality in-home care who will take the time to learn about your requirements and treat you with kindness and respect.

Assisting Hands will collaborate with veterans and their families to assess their care requirements and figure out how your VA benefits can cover the cost of home care.

Assisting Hands Home Care will begin with a complimentary in-home evaluation to analyze your care needs and VA benefits to see how they can be used for home care. If you are a veteran or the spouse of a veteran and are qualified for a VA pension, Assisting Hands Home Care is ready to help you to understand how your VA benefits can be applied to our veteran home care programs.

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First Oral Medication to Treat Moderate-to-Severe Crohn’s Disease Completes Successful Phase 3 Trial and Earns FDA Approval

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“This therapy has the potential to transform the lives of individuals battling this chronic condition and offers a new hope for improved quality of life,” said Jean-Frederic Colombel, MD, co-Director, Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center, The Mount Sinai Hospital.


NEW YORK (PRWEB)

Patients with moderate-to-severe Crohn’s disease now have a new treatment option to suppress their intestinal inflammation and painful symptoms, and help them maintain their relief.

Data from a phase 3 trial published today in The New England Journal of Medicine show that upadacitinib—a breakthrough, once-daily oral medication—helps patients achieve and maintain clinical and endoscopic remission. As a result, upadacitinib garnered Food and Drug Administration approval on Thursday, May 18.

Crohn’s disease, a chronic inflammatory bowel disorder affecting millions worldwide, has long presented a significant challenge for both patients and health care providers. Existing treatment options often fall short in achieving sustained remission and controlling symptoms. However, the results of the upadacitinib study herald a promising breakthrough in managing this complex condition.

Corresponding author Jean-Frederic Colombel, MD, notes, “Upadacitinib addresses an unmet need in the treatment of Crohn’s disease and allows patients access to an oral medication that could put them in clinical and endoscopic remission. This therapy has the potential to transform the lives of individuals battling this chronic condition and offers a new hope for improved quality of life.” Dr. Colombel is the co-Director of the Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center at The Mount Sinai Hospital in New York City and Professor of Medicine (Gastroenterology) at the Icahn School of Medicine at Mount Sinai.

Upadacitinib is a selective Janus kinase (JAK) inhibitor. It precisely targets the underlying pathways of inflammation, thereby mitigating the symptoms and potentially minimizing the risk of adverse events associated with immunosuppression.

The study spanned 43 countries and 277 sites, and enrolled a diverse group of patients 18 to 75 years old who had moderate-to-severe Crohn’s disease for at least three months.

Participants were randomly assigned to receive 45 mg of upadacitinib or placebo (2:1) for induction therapy to assess its effectiveness in achieving remission in two double-blind phase 3 trials, U-EXCEL and U-EXCEED. The medication was taken once daily for 12 weeks. Patients who had a clinical response to upadacitinib induction therapy were then randomly assigned in the U-ENDURE maintenance trial to receive 15 mg or 30 mg of upadacitinib, or placebo (1:1:1) once daily for 52 weeks. The maintenance phase evaluated the drug’s ability to sustain remission and prevent relapse. (U-EXCEED had an additional 12-week open-label, active single-group induction period to allow for the accrual of enough patients for entry into U-ENDURE.)

The primary endpoints for induction (week 12) and maintenance (week 52) were clinical remission (defined as a Crohn’s Disease Activity Index score of less than 150 on a range of 0 to 600, with higher scores indicating more severe disease activity) and endoscopic response (defined as a decrease in the Simple Endoscopic Score for Crohn’s Disease [SES-CD; range, 0 to 56, with higher scores indicating more severe disease] of greater than 50% from baseline of the induction trial [or for patients with an SES-CD of 4 at baseline, a decrease of greater than or equal to 2 points from baseline]).

Upadacitinib demonstrated superior efficacy over placebo, with a statistically significant proportion of patients achieving clinical remission after induction therapy. During the maintenance phase, the therapy substantially reduced the rate of disease relapse, illustrating its potential as a long-term treatment option for Crohn’s disease.

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About the Mount Sinai Health System

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, over 400 outpatient practices, nearly 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it.

Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,300 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report’s Best Hospitals, receiving high “Honor Roll” status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children’s Hospital among the country’s best in several pediatric specialties.

For more information, visit https://www.mountsinai.org or find Mount Sinai on Facebook, Twitter and YouTube.

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