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Miriam Merad, MD, PhD, Elected to the National Academy of Medicine for Seminal Work in Immunology and Cell Biology


Miriam Merad, MD, PhD, an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology. Dr. Merad was elected for her transformational discoveries, establishing for the first time that tissue-resident macrophages have distinct origins, maintain their lineage separately from adult hematopoiesis, and possess unique functions that enhance tissue health, repair, infection defense, and impact tumor outcomes. She is the Mount Sinai Professor in Cancer Immunology, Chair of the Department of Immunology and Immunotherapy, Director of the Marc and Jennifer Lipschultz Precision Immunology Institute, and Director of the Human Immune Monitoring Center at Icahn Mount Sinai.

NEW YORK, Oct. 9, 2023 /PRNewswire-PRWeb/ — Miriam Merad, MD, PhD, an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology.

Dr. Merad was elected for her transformational discoveries, establishing for the first time that tissue-resident macrophages have distinct origins, maintain their lineage separately from adult hematopoiesis, and possess unique functions that enhance tissue health, repair, infection defense, and impact tumor outcomes.

She is the Mount Sinai Professor in Cancer Immunology, Chair of the Department of Immunology and Immunotherapy, Director of the Marc and Jennifer Lipschultz Precision Immunology Institute, and Director of the Human Immune Monitoring Center at Icahn Mount Sinai.

With this appointment, Dr. Merad joins an elite group of distinguished international scientists alongside 100 new members this year. Election to the Academy is considered one of the highest honors a scientist can receive in health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.

“This honor underscores Dr. Merad’s profound impact on these fields,” said Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of Icahn Mount Sinai and President for Academic Affairs of the Mount Sinai Health System. “Dr. Merad’s groundbreaking discoveries have reshaped the landscape of medical treatments, while her ongoing work continues to uncover the intricate responses of the human immune system to disease.”

In a 2010 Science study, Dr. Merad revealed that tissue-resident embryonic precursors give rise to macrophages, large white blood cells that play crucial roles in organ health and disease. This landmark research, cited thousands of times, has reshaped immunology textbooks and ignited an effort worldwide to explore tissue-resident macrophages in all areas of medicine. Dr. Merad’s own team has revealed the role of the different macrophage lineages in cancer progression, treatment response, and inflammatory bowel disease in prominent journals, including Science, Cell, and Nature.

She has also made significant contributions to research on dendritic cells, a group of cells that control adaptive immunity. She identified a new subset of dendritic cells that has now become a key target to enhance viral and antitumor immunity. In a May 2020 Nature study, her team uncovered new therapeutic targets to boost dendritic cell-mediated antitumor immunity, and in a more recent paper also published in Nature this year, showed that this new therapeutic target can help treat patients with lung cancer.

Dr. Merad has transformed Mount Sinai into a global hub for studying the human immune system. She established the cutting-edge Human Immune Monitoring Center (HIMC), a world-leading research facility using single-cell technology to investigate immune cell contributions to human diseases and treatments. HIMC participates in consortia funded by the National Institutes of Health. This center is now pivotal in identifying new immune targets of cancer and inflammatory diseases.

“I am deeply humbled to be part of the National Academy of Medicine. Being elected is an incredible honor, and I’m proud to represent Mount Sinai,” said Dr. Merad, who joined Mount Sinai’s faculty in 2004. Raised by parents who were both scientific and medical professionals educated in France and practicing in Algeria, she was instilled with a deep respect for the transformative potential of science. She also attributes her success to Mount Sinai, which she said has provided her with the freedom to grow and pursue her research. Dr. Merad emphasizes the institution’s culture of empowering junior faculty and young scientists: “If you aspire to innovate early in your career, Mount Sinai is the place to be.”

The election of Dr. Merad brings Mount Sinai’s total membership in the prestigious group to 26 current and emeritus faculty members. The others are Joseph D. Buxbaum, PhD • Yvette Calderon, MD, MS • Neil S. Calman, MD • Brendan Carr, MD, MS • Dennis S. Charney, MD • Judy Cho, MD • Kenneth L. Davis, MD • Robert J. Desnick, MD, PhD • Angela Diaz, MD, MPH • Valentin Fuster, MD, PhD • Bruce Gelb, MD • Alison M. Goate, DPhil • Yasmin L. Hurd, PhD • Philip J. Landrigan, MD, MSc • Helen S. Mayberg, MD • Diane E. Meier, MD • Eric J. Nestler, MD, PhD • Maria Iandolo New, MD • Peter Palese, PhD • Ramon E. Parsons, MD, PhD • Lynne D. Richardson, MD • Hugh A. Sampson, MD • Albert Siu, MD, MSPH • Barbara G. Vickrey, MD, MPH • Rachel Yehuda, PhD.

Dr. Merad was previously elected to the National Academy of Sciences (NAS) in 2020, one of a very few Icahn Mount Sinai faculty members to hold dual Academy memberships.

New members of the Academy are elected by current members through a process that recognizes individuals who have made major contributions to the advancement of the medical sciences, health care, and public health. For more details, see this year’s official announcement from the National Academy of Medicine: https://nam.edu/news/.

About the Icahn School of Medicine at Mount Sinai
The Icahn School of Medicine at Mount Sinai is internationally renowned for its outstanding research, educational, and clinical care programs. It is the sole academic partner for the eight- member hospitals* of the Mount Sinai Health System, one of the largest academic health systems in the United States, providing care to a large and diverse patient population.

Ranked 14th nationwide in National Institutes of Health (NIH) funding and among the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges, Icahn Mount Sinai has a talented, productive, and successful faculty. More than 3,000 full-time scientists, educators, and clinicians work within and across 44 academic departments and 36 multidisciplinary institutes, a structure that facilitates tremendous collaboration and synergy. Our emphasis on translational research and therapeutics is evident in such diverse areas as genomics/big data, virology, neuroscience, cardiology, geriatrics, as well as gastrointestinal and liver diseases.

Icahn Mount Sinai offers highly competitive MD, PhD, and Master’s degree programs, with current enrollment of approximately 1,300 students. It has the largest graduate medical education program in the country, with more than 2,000 clinical residents and fellows training throughout the Health System. In addition, more than 550 postdoctoral research fellows are in training within the Health System.

A culture of innovation and discovery permeates every Icahn Mount Sinai program. Mount Sinai’s technology transfer office, one of the largest in the country, partners with faculty and trainees to pursue optimal commercialization of intellectual property to ensure that Mount Sinai discoveries and innovations translate into healthcare products and services that benefit the public.

Icahn Mount Sinai’s commitment to breakthrough science and clinical care is enhanced by academic affiliations that supplement and complement the School’s programs.

Through the Mount Sinai Innovation Partners (MSIP), the Health System facilitates the real-world application and commercialization of medical breakthroughs made at Mount Sinai. Additionally, MSIP develops research partnerships with industry leaders such as Merck & Co., AstraZeneca, Novo Nordisk, and others.

The Icahn School of Medicine at Mount Sinai is located in New York City on the border between the Upper East Side and East Harlem, and classroom teaching takes place on a campus facing Central Park. Icahn Mount Sinai’s location offers many opportunities to interact with and care for diverse communities. Learning extends well beyond the borders of our physical campus, to the eight hospitals of the Mount Sinai Health System, our academic affiliates, and globally.

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  • Mount Sinai Health System member hospitals: The Mount Sinai Hospital; Mount Sinai Beth Israel; Mount Sinai Brooklyn; Mount Sinai Morningside; Mount Sinai Queens; Mount Sinai South Nassau; Mount Sinai West; and New York Eye and Ear Infirmary of Mount Sinai.

Media Contact

Karin Eskenazi, Mount Sinai, 332-257-1538, [email protected], mountsinai.org

SOURCE Mount Sinai

Phase 2a Study of HU6, Rivus Pharmaceuticals' Investigational Controlled Metabolic Accelerator, Demonstrates Clinical Benefit in Patients with High Body Mass Index and Nonalcoholic Fatty Liver Disease



– Results showing significant reductions in liver fat content and body weight, no loss of lean muscle mass, and improvement in key markers of metabolism and inflammation published in The Lancet Gastroenterology & Hepatology – – HU6 was well tolerated at once-daily oral doses with adverse…

Allegheny Health Network honored by AMA for promoting well-being of health care workers


In 2023, a total of 72 hospitals and health care organizations nationwide earned recognition through documented efforts to reduce system-level drivers of burnout and demonstrated competencies in commitment, assessment, leadership, efficiency of practice environment, teamwork, and support.

Those winners were recognized in gold, silver and bronze categories – AHN was one of 26 organizations to receive a silver-level recognition.

“At AHN, we recognize that our community’s health depends on the well-being of our health care workforce, which is why we’re working so hard to mitigate work-related clinician burnout and promote clinical wellness at all professional levels, and at all sites of care,” said Thomas Campbell, MD, AHN vice president and medical director of Clinician Wellness. “While we know that this is an ongoing improvement journey, we’re thrilled to be recognized by the AMA for our achievements in 2023.”

Burnout rates among the nation’s physicians and other health care professionals spiked dramatically as the COVID-19 pandemic placed acute stress on care teams and exacerbated long-standing system issues. While the worst days of the pandemic have passed, the lingering impact of work-related burnout remains an obstacle to achieving national health goals.

“Health organizations that have earned recognition from the AMA’s Joy in Medicine Health System Recognition Program are leading a national movement that has declared the well-being of health professionals to be an essential element for providing high-quality care to patients, families, and communities,” said AMA President Jesse M. Ehrenfeld, MD, MPH. “Each ‘Joy in Medicine’-recognized organization is distinguished as among the nation’s best at creating a culture of wellness that makes a difference in the lives of clinical care teams.”

At AHN, the wellness team measures burnout symptoms through extensive annual surveys. For every category of clinician surveyed – physician, advanced practice provider, nurse, nurse manager, and resident – AHN’s burnout rates are well below the national rates for 2023. Additionally, from 2022 to 2023, self-reported burnout rates dropped for AHN physicians, APPs, nurse managers, and nurses.

Notably, nursing burnout rates at AHN have dropped by 35 percent since 2021. In that time, AHN has implemented a number of wellness strategies, and has worked with counterparts at Highmark Health to reimagine the nursing profession, allowing for more flexible work shifts and creating remote nursing teams.

One of the unique features of AHN’s wellness survey is that it includes team members from across the network — not just clinicians, techs and patient-facing caregivers, but also non-patient-facing team members, such as those in billing or information services. AHN also surveys support staff, such as environmental services workers, nutrition workers and cafeteria staff, security, and transport workers.

“The factors behind a physician’s burnout are going to be much different than someone working in nutrition,” said Donald Whiting, MD, chief medical officer for AHN. “Surveying everyone allows us to create a much more accurate portrait of wellness across our entire organization.”

The survey also illustrates that there’s no magic pill for relieving burnout across the medical professions — physicians in the ICU might feel burnout more acutely, and for different reasons, than those working in radiology or an outpatient setting. Nurses working the overnight shift might worry about emergency room safety, while those working during the day might be so busy that they don’t have time to take water breaks.

“Listening to all those different concerns, and following through on the issues raised, makes a huge difference for our caregivers — and ultimately for our patients,” said Michele Tucci, senior vice president, Executive Strategic Programs for AHN.

Since its inception in 2019, the Joy in Medicine™ Health System Recognition Program has recognized just over 100 organizations across the country.

“The goal of the Joy in Medicine Health System Recognition Program is to unite the health care community in building a nationwide culture committed to the well-being of clinical care teams by helping health organizations invest in action plans promoting professional fulfillment and meaning that clinicians find in caring for their patients,” said Christine Sinsky, MD, AMA vice president of professional satisfaction.

Learn more about the AMA Joy in Medicine™ Health System Recognition Program at ama-assn.org/joyinmedicine. The AMA is a professional association for physicians and medical students that promotes the art and science of medicine and advocates for the betterment of public health.

Media Contact

Sarafina Brooks James, Allegheny Health Network, 412- 609-2902, [email protected], https://www.ahn.org

SOURCE Allegheny Health Network

Everest Medicines' Partner Calliditas Presents New Data from the NefIgArd Phase 3 Trial at the 17th International Symposium on IgA Nephropathy Tokyo 2023


SHANGHAI, Oct. 4, 2023 /PRNewswire/ — Everest Medicines’ (HKEX 1952.HK, “Everest”, or the “Company”) partner Calliditas Therapeutics AB (Nasdaq: CALT, Nasdaq Stockholm: CALTX) (“Calliditas”) presented new biomarker and subgroup analyses from Nefecon®’s Phase 3 NefIgArd study in both…

Advantages and Challenges in Pre-clinical and Clinical Development, Upcoming Webinar Hosted by Xtalks


Join this informative webinar to gain insights into the best use of PCR methods in the pre-clinical and clinical development of vaccines and other biotherapeutics.

Join Manisha R. Diaz, PhD, Associate Director of Research and Development, Eurofins Viracor BioPharma Services; Deepak Tomar, PhD, Senior Scientific Lab Lead, Eurofins Bioanalytical Services; and Erik Jerks, PhD, Director of Bioanalytical Services, Eurofins Bioanalytical Services, for the live webinar on Friday, October 13, 2023, at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit dPCR, qPCR and RT-qPCR: Advantages and Challenges in Pre-clinical and Clinical Development.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

Media Contact

Vera Kovacevic, Xtalks, +1 (416) 977-6555 x371, [email protected]

SOURCE Xtalks

Global Liquid Dosage Excipients Market Research Report 2023: Burgeoning Opportunities in mRNA-based Therapeutics & Increasing Need for an Independent Approval Pathway for Novel Excipient Development



DUBLIN, Oct. 3, 2023 /PRNewswire/ — The “Global Liquid Dosage Excipients Growth Opportunities” report has been added to ResearchAndMarkets.com’s offering. The global study on the liquid dosage excipients assesses growth opportunities in the oral liquid and parenteral excipients market…

Ink Different Tattoos Teams Up With The Red Cross For “Holiday For Heroes” Nationwide Campaign To Support The Armed Service Members


From Oct 1st – Oct 15th, dedicated donation boxes can be found at all Ink Different tattoo shops across the country to give tattoo clients and the local community the opportunity to make a meaningful difference in the lives of local heroes and contribute to this heartwarming cause.

You can participate by bringing items that are specifically needed. The American Red Cross has provided a list of essentials to guide your donations, ensuring that our heroes receive exactly what they require:

  • Decks of playing cards and fidget spinners
  • Gum, mints, hard candy (no chocolate)
  • Individual packets of flavored drink mixes (Crystal Light, electrolytes)
  • Individual packets of powdered hot cocoa or apple cider mix
  • *Individually packaged/travel-size snacks (nuts, trail mix, beef jerky, Slim Jim)
  • *Protein bars, granola bars, breakfast bars
  • *Non-perishable meat (individual packets of tuna, chicken, salmon; not canned)
  • Holiday cards and letters of appreciation (Please do not use glitter or write the date, your last name, address or personal contact information. Please use wording that will encompass the holiday spirit without reference to religion as these will go to a diverse group of service members.)

For those who prefer to make financial contributions, Ink Different is teaming up with the Red Cross for the long haul as the first nationwide tattoo company to partner with the Red Cross to support the armed forces.

“The Red Cross is near and dear to all of us for different reasons,” shares Paul-Anthony, “With a dedicated fundraising page that we can promote in our studios nationwide to every tattoo client, every day, we hope to ensure regular donations that make a difference.”

“In an ever-changing world where the resilience of our communities are constantly challenged, the importance of steadfast partnerships with organizations dedicated to humanitarian relief cannot be overstated. Our partnership with the American Red Cross is not just a seasonal endeavor but a permanent commitment,” shares Gabe Jaksich, Ink Different’s National Program Director for Ink Different’s nationwide tattoo apprenticeship program. “Together, we will be supporting the heroes, like my son, who selflessly protect and serve our nation throughout the year.”

To contribute directly and support the “Holiday for Heroes” stop by any of Ink Different’s Tattoos locations nationwide.

You can visit https://www.redcross.org/donate/cm/inkdifferent-pub.html/ to make financial contributions.

Media Contact

Benny Hiraldo, Ink Different Tattoos, 1 1-917-227-2842, [email protected], https://inkdifferenttattoos.com/

SOURCE Ink Different Tattoos