Compared to conventional culture and antibiotic susceptibility testing, this rapid turnaround allows the microbiology lab to deliver results to the clinical teams more efficiently to allow for prompt administration of the correct regimen of antibiotics and antifungals.
TORONTO (PRWEB)
November 18, 2022
With the recent improvements of molecular blood culture identification (BCID) panels, time to pathogen and resistance profile identification generated from a positive blood culture has been drastically reduced. Compared to conventional culture and antibiotic susceptibility testing, this rapid turnaround allows the microbiology lab to deliver results to the clinical teams more efficiently to allow for prompt administration of the correct regimen of antibiotics and antifungals. More specifically when looking at gram-negative (GN) pathogens, organisms harboring extended-spectrum beta-lactamases (ESBL), can be reported within three hours after a blood culture turns positive and the molecular test, inclusive of genotypic resistance genes, such as CTX-M, can be reported out at Northwell Health Laboratories. Until now, the clinical impact remained unclear.
At Northwell Health, an 11 hospital system, a retrospective analysis of adult hospitalized patients with bacteremia due to ESBL producing organisms was conducted to detail pre-implementation of the ePlex® Blood Culture Identification (BCID) Panels (Jan-Sep 2019) versus post-implementation (Jan-Sep 2021). Time to appropriate therapy, total antibiotic use, length of stay, mortality and 30-day readmission were assessed during the study. Out of a total of 503 patient initial encounters, 281 were included after inclusion and exclusion criteria were applied.
In this webinar, Dr. Aya Haghamad, a Pharmacy Advisor at Northwell Health, will highlight the hospital networks experience implementing the ePlex BCID-GN Panel and the outcomes they experienced from a clinical perspective. She will detail the significant improvements in time to appropriate therapy that were observed after the addition of a rapid molecular test for ESBL was instituted in this large hospital network.
Register to learn about the clinical impact of early detection of ESBL bacteremia in hospitalized patients.
Join Aya Haghamad, PharmD, Advisor, Pharmacy, Pathology Informatics, for the live webinar on Monday, December 5, 2022, at 11am EST (4pm GMT/UK).
For more information, or to register for this event, visit The Clinical Impact of Early Detection of Extended-Spectrum Beta Lactamase (ESBL) Bacteremia in Hospitalized Patients.
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