Grid Biosciences Announces License Agreement with NIH for Epstein-Barr Virus Vaccine


Grid Biosciences (“Grid”), a biotechnology company, today announced the signing of a license agreement for the development of a vaccine against Epstein-Barr virus (“EBV”) with the National Institute of Allergy and Infectious Diseases (“NIAID”), part of the National Institutes of Health (“NIH”). The agreement includes access to NIH’s patent rights in EBV envelope proteins that the virus uses to gain entry into human cells.

The agreement allows Grid to use these materials and patent rights owned by the NIH for the worldwide development, manufacture, and commercialization of EBV vaccines for the protection from viral infection and diseases associated with EBV. EBV is the causative agent of infectious mononucleosis and is associated with certain malignancies and autoimmune diseases, such as nasopharyngeal carcinoma, gastric cancer, Hodgkin’s Lymphoma, Burkitt’s lymphoma, and multiple sclerosis. There are no vaccines nor targeted therapies currently licensed for EBV infection.

To date, Dr. Jeffrey Cohen, Chief of the Laboratory of Infectious Diseases, and his laboratory in collaboration with the Vaccine Research Center at NIAID, have designed and constructed EBV vaccine candidates that employ fusion proteins consisting of the immunogenic portions of EBV envelope proteins. In preclinical testing, these vaccine candidates elicited neutralizing antibody titers in immunized mice which were substantially higher than those seen in humans naturally infected with EBV.

Daniel-Joseph Leung, Ph.D., CEO of Grid, commented, “This agreement paves the way for us to advance the development of Dr. Cohen and the NIH’s extraordinary work. It is an important step towards protecting people worldwide from infectious diseases.”

Additional terms of the agreement were not disclosed.

Forward-Looking Statements:

The forward-looking statements in this press release are neither promises nor guarantees, and they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Grid’s control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. The forward-looking statements in this press release are based on information available to Grid as of the date hereof.

Contact:

For Grid Biosciences

Robert (RAS) Sheffield

+1-646-902-1318

ras@rasheffield.com

http://www.gridbiosciences.com

For NIAID/NIH

National Institute of Allergy and Infectious Diseases

+1-301-402-1663

niaidnews@niaid.nih.gov

https://www.niaid.nih.gov

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