What neuroscience teams want to achieve logically and computationally requires infrastructure, communication, and organization across departments. Commercial companies can provide computation as a service rather than having each lab reproduce the same computation with graduate students.
TAMPA BAY, Fla. (PRWEB)
August 23, 2022
In 2013, then-President Obama launched the brain initiative, which allocated funding to map every neuron in the brain. Understanding how the brain works can revolutionize the lives of many Americans, solving the complex problems of Alzheimer’s and Parkinson’s disease, depression, and traumatic brain injury (1). However, mapping the brain alone does not reveal how it functions. Different parts of the brain appear similar but function differently, and each person has unique brain anatomy (2).
Neuroscientists have historically worked alone on individual projects, but as technology and data advance, they have to team up to achieve meaningful results. The need for data analysis has allocated neuroscience graduate students to solving complex computer science problems. This presents two significant problems. First, the number of years to achieve a neuroscience Ph.D. is increasing. Second, each graduate student solves the problems presented to them in isolation, which fails to create continuity either after they leave or between research teams. The result is a vast amount of available data failing to achieve its potential. Enter “stabilizing” disruptor Dimitri Yatsenko, CEO of DataJoint, who explains to Karla Jo Helms, host of the Disruption Interruption podcast, that to be used effectively for the greater good, the vast data recorded about the brain has to be analyzed with continuity between universities, laboratories, and research teams.
Dimitri Yatsenko’s background in computer science gave him a unique perspective when his fascination with the human brain led him to neuroscience. He saw independent labs repeatedly reinventing ways of doing data analysis, weighing grad students down with data analysis that had little to do with their passions, and falling short of their collaborative potential. Dimitri said to himself, THAT’S IT — I’M DONE WITH THE STATUS QUO and began to develop a computational framework to create continuity across projects, teams, and applications. He made it cloud compatible, containerized, and web-accessible so it can be quickly deployed for multi-lab collaborations, and DataJoint was born.
Dimitri explains:
We have more data gathered about the brain and its circuits than at any other time in history. We need to combine molecular, genetic, and electrophysiology data, which is beyond the scope of any single neuroscientist. Understanding the brain requires a systematic approach to data and modeling.
Progress is limited by the tsunami of data and the systems required to model and analyze it.
Up to half of the time spent on any neuroscience project is software engineering and systems engineering.
Neuroscientists are fundamentally curious about how the brain, its circuits, our interaction with the environment, and our genetic programming work to produce intelligence. However, the next level of understanding relates to how molecules, genes, and stimuli interact to shape circuits and how circuit systems produce adaptive behavior.
The brain is complex but has patterns to it. You can make the same circuits of the neocortex (the outer portion of the mammalian brain) solve very different problems. The more we understand the principles of how this works, the more effectively we can apply machine learning to understand how circuits and populations of neurons work together in the living brain.
What neuroscience teams want to achieve logically and computationally requires infrastructure, communication, and organization across departments. They haven’t had the tools to support this requirement, and it’s adding to the overhead costs of research.
Commercial companies can help execute things more effectively and provide computation as a service rather than having each lab reproduce the same computation with graduate students.
DataJoint provides a systematic framework to work with data and computation and bridge communication gaps in one unified framework.
Disruption Interruption is the podcast where you’ll hear from today’s biggest Industry Disruptors. Learn what motivated them to bring about change and how they overcome opposition to adoption.
Disruption Interruption can be listened to via the Podbean app, and is available on Apple’s App Store and Google Play.
About Disruption Interruption:
Disruption is happening on an unprecedented scale, impacting all manner of industries — MedTech, Finance, IT, eCommerce, shipping and logistics, and more — and COVID has moved their timelines up a full decade or more. But WHO are these disruptors, and when did they say, “THAT’S IT! I’VE HAD IT!”? Time to Disrupt and Interrupt with host Karla Jo “KJ” Helms, veteran communications disruptor. KJ interviews bad a**es who are disrupting their industries and altering economic networks that have become antiquated with an establishment resistant to progress. She delves into uncovering secrets from industry rebels and quiet revolutionaries that uncover common traits — and not-so-common — that are changing our economic markets … and lives. Visit the world’s key pioneers that persist to success, despite arrows in their backs at http://www.disruptioninterruption.com.
About Karla Jo Helms:
Karla Jo Helms is the Chief Evangelist and Anti-PR™ Strategist for JOTO PR Disruptors™.
Karla Jo learned firsthand how unforgiving business can be when millions of dollars are on the line — and how the control of public opinion often determines whether one company is happily chosen or another is brutally rejected. Being an alumnus of crisis management, Karla Jo has worked with litigation attorneys, private investigators, and the media to help restore companies of goodwill back into the good graces of public opinion — Karla Jo operates on the ethic of getting it right the first time, not relying on second chances and doing what it takes to excel. Helms speaks globally on public relations, how the PR industry itself has lost its way, and how, in the right hands, corporations can harness the power of Anti-PR to drive markets and impact market perception.
About DataJoint:
Dimitri Yatsenko is the Chief Executive Office at DataJoint, which is the leading data analysis platform and toolkit for neurophysiology researchers. They develop data science frameworks, platforms, and services for collaborative research, focusing on neuroscience and AI.
With a Ph.D. in Neuroscience (Baylor College of Medicine) and M.S. in Computational Engineering and Science (University of Utah), Dimitri holds an extensive record of projects in academia and industry in areas of signal analysis and image processing, machine learning, medical imaging, data science, and neurophysiology. While engaged in neuroscience research at Baylor College of Medicine, Dimitri started the DataJoint framework as an open source framework — https://datajoint.org. Researchers turned to the project to organize a computational data pipeline spanning multiple labs. After receiving his Ph.D., Dimitri co-founded DataJoint to develop solutions and services for data-driven team science to bridge both social and technical gaps. For more information, visit https://www.datajoint.com
Sources:
1. Obama White House Archives; “THE BRAIN INITIATIVE. Brain Research through Advancing Innovative Neurotechnologies.” Retrieved 11 August 2022, obamawhitehouse.archives.gov/BRAIN.
2. University of Zurich. “Every person has a unique brain anatomy.” ScienceDaily. ScienceDaily, 10 July 2018.