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Methylome Profiling and Biomarker Discovery Using MeDIP-Seq from Liquid Biopsy Samples, Upcoming Webinar Hosted by Xtalks

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Cell-free methylated DNA (cfMeDNA) immunoprecipitation and high throughput sequencing (cfMeDIP-seq) is a highly sensitive, novel technique for non-invasive cancer detection and classification via identification of tumor-specific methylation patterns in cell-free DNA (cfDNA).


TORONTO (PRWEB)

Epigenetic modifications, such as DNA methylation, have emerged as novel and promising key areas of cancer research in a liquid biopsy with broad potential applications in early cancer detection, risk assessment, prognosis and prediction of response to therapy.

Cell-free methylated DNA (cfMeDNA) immunoprecipitation and high throughput sequencing (cfMeDIP-seq) is a highly sensitive, novel technique for non-invasive cancer detection and classification via identification of tumor-specific methylation patterns in cell-free DNA (cfDNA).

CfDNA methylation profiling provides several advantages over the methods based on somatic mutations. DNA methylation is a tissue-specific and stable epigenetic mark that allows one to determine the tissue of origin. In addition, each tumor type has a specific and defined methylome profile of hypermethylation of the CpG island in tumor-suppressor genes, which distinguishes cancer tissue from healthy tissue.

Register for this webinar to hear a discussion about the applications and analysis of cfMeDIP-seq in liquid biopsy with a special interest in cancer detection.

Join Pier Vitale Nuzzo, research fellow; and Sandor Spisak, Instructor in Medicine, Department of Medical Oncology, both from the Dana-Farber Cancer Institute, Harvard Medical School, for the live webinar on Thursday, September 9, 2021 at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit Methylome Profiling and Biomarker Discovery Using MeDIP-Seq from Liquid Biopsy Samples.

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