A critical balance of low energy consumption, longevity, and temperature performance make for the best COVID-19 vaccine ULT freezer.
January 08, 2021
mRNA vaccine research conducted prior to COVID-19’s arrival allowed scientists to devise mechanisms to stably deliver mRNA molecules into cells, once injected with a syringe. Compared to traditional vaccine development, mRNA vaccines are relatively simple to design and manufacture. This made them leading candidates in the urgent race for a COVID-19 vaccine. However, maintaining mRNA stability while outside our bodies presents a multitude of logistical hurdles, each requiring careful attention.
RNA utilized in research and clinical laboratories is traditionally stored in -80°C freezers. These ultra-low temperatures (ULT) cease molecular movement and enzyme activity in mRNA samples, preserving their structure and function for many years. An ultra-low temperature freezer is a staple in every life science laboratory, but in clinics and hospitals where conventional vaccines are stored at 5°C, specialized freezers do not exist. To add to the complexity, two leading mRNA vaccine manufacturers will require two separate temperature storage points (-20°C and -80°C), requiring separate, specialized units.
Vaccine administration sites must quickly equip their facilities with new cold storage equipment. The inability of an ultra-low temperature freezer to provide stable temperatures at a -80°C setpoint may compromise the vaccine’s viability, leading to improper immunization of the public. A critical balance of low energy consumption, longevity, and temperature performance make for the best COVID-19 vaccine ULT freezer.
Join featured speakers from PHCNA, Carl Radosevich, Senior Manager, Scientific Applications & Collaborations; and Joe LaPorte, Director, Projects and Regulatory, in a live webinar on Tuesday, January 19, 2021 at 1pm EST.
For more information, or to register for this event, visit COVID-19 Vaccine Storage: Addressing the Challenges of mRNA-Based Vaccine Storage at Ultra-Low Temperatures.
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